抗原部位 |
a.a.25-467
|
種由来 |
Human
|
精製度 |
Affinity Purified
|
適用 |
Western Blot Immunohistochemistry
|
免疫動物 |
Mouse
|
抗体クラス |
IgG1
|
クローン |
OTI1E5
|
交差種 |
Human
|
Accession No.(Gene/Protein) |
NM_006928, P40967
|
Gene Symbol |
PMEL
|
使用目的 |
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan
|
その他 |
[locus ID]6490
|
※サムネイル画像をクリックすると拡大画像が表示されます。
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SILV (RC200663, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SILV. Positive lysates LY402062 (100ug) and LC402062 (20ug) can be purchased separately from OriGene.
|
|
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SILV (RC200663, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SILV. Positive lysates LY402062 (100ug) and LC402062 (20ug) can be purchased separately from OriGene.
|
|
|
メーカー |
品番 |
包装 |
ORG
|
TA803054
|
100 UL
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
約10日
|
保存温度 |
-20℃
|
|