抗原部位 |
a.a.104-471
|
種由来 |
Human
|
精製度 |
Affinity Purified
|
適用 |
Western Blot Immuno Fluorescence
|
免疫動物 |
Mouse
|
抗体クラス |
IgG1
|
クローン |
OTI4B7
|
交差種 |
Human Mouse Rat
|
Accession No.(Gene/Protein) |
NM_002427, P45452
|
Gene Symbol |
MMP13
|
分子量 |
42.2 kDa
|
使用目的 |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].
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その他 |
[locus ID]4322
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※サムネイル画像をクリックすると拡大画像が表示されます。
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP13 (RC224156, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP13. Positive lysates LY400869 (100ug) and LC400869 (20ug) can be purchased separately from OriGene.
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP13 (RC224156, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP13. Positive lysates LY400869 (100ug) and LC400869 (20ug) can be purchased separately from OriGene.
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|
メーカー |
品番 |
包装 |
ORG
|
TA506804
|
100 UL [1 mg/ml]
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
約10日
|
保存温度 |
-20℃
|
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