| 種由来 |
Human
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| 精製度 |
Affinity Purified
|
| 適用 |
Western Blot
Immunohistochemistry
Immuno Fluorescence
|
| 免疫動物 |
Rabbit
|
| 抗体クラス |
IgG
|
| 交差種 |
Human
Mouse
|
| Accession No.(Gene/Protein) |
NM_133477, Q9UMS6
|
| Gene Symbol |
Synaptopodin 2
|
| 使用目的 |
SYNPO2 Antibody: SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.
|
| その他 |
[locus ID]171024
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※サムネイル画像をクリックすると拡大画像が表示されます。
Western blot analysis of SYNPO2 in human skeletal muscle tissue lysate with SYNPO2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Western blot analysis of SYNPO2 in human skeletal muscle tissue lysate with SYNPO2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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| メーカー |
品番 |
包装 |
|
ORG
|
TA320130
|
100 UG
[1ug/ul]
|
※表示価格について
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