種由来 |
Human
|
精製度 |
Affinity Purified
|
適用 |
Western Blot
|
免疫動物 |
Rabbit
|
抗体クラス |
IgG
|
交差種 |
Human Mouse
|
Accession No.(Gene/Protein) |
NM_001134647, Q8N556
|
Gene Symbol |
AFAP1
|
使用目的 |
AFAP1 Antibody: The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.
|
その他 |
[locus ID]60312
|
※サムネイル画像をクリックすると拡大画像が表示されます。
Western blot analysis of AFAP1 in Hela cell lysate with AFAP1 antibody at (A) 1 and (B) 2 ug/mL.
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Western blot analysis of AFAP1 in Hela cell lysate with AFAP1 antibody at (A) 1 and (B) 2 ug/mL.
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|
メーカー |
品番 |
包装 |
ORG
|
TA319994
|
100 UG [1ug/ul]
|
※表示価格について
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