種由来 |
Human
|
精製度 |
Affinity Purified
|
適用 |
Western Blot Immunohistochemistry
|
免疫動物 |
Rabbit
|
抗体クラス |
IgG
|
交差種 |
Human Mouse Rat
|
Accession No.(Gene/Protein) |
NM_004879, O14681
|
Gene Symbol |
EI24
|
使用目的 |
EI24 Antibody: The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.
|
その他 |
[locus ID]9538
|
※サムネイル画像をクリックすると拡大画像が表示されます。
Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 ug/mL.
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Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 ug/mL.
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|
メーカー |
品番 |
包装 |
ORG
|
TA319782
|
100 UG [1ug/ul]
|
※表示価格について
|