| 別品名 |
Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
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| 種由来 |
Human
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| 由来詳細 |
Recombinant
|
| Accession No.(Gene/Protein) |
O75339
|
| Gene Symbol |
CILP
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| タグ（タンパク質） |
問い合わせ
|
| 発現系 |
酵母
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| 発現領域 |
問い合わせ
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| 分子量 |
53.7 kDa
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| その他 |
[Buffer]Tris-based buffer, 50% glycerol
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| 参考文献 |
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. Gray A.M.Genome Res. 13:2265-2270(2003)
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| [注意事項] |
本商品は受注生産品です。Tagは製造過程で決定されます。特定のTagをご希望の場合にはお問合せください。tag-freeの場合もあります。
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※サムネイル画像をクリックすると拡大画像が表示されます。
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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|
| メーカー |
品番 |
包装 |
|
CSB
|
CSB-YP005437HU
|
1 MG
|
※表示価格について
| 当社在庫 |
なし
|
| 納期目安 |
約1.5ヶ月
|
| 保存温度 |
-２０℃
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