別品名 |
Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein, EBI3, EBI-3, IL-35, IL35
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種由来 |
Mouse
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標識物 |
Biotin
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精製度 |
Ig fraction - Protein A
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適用 |
Neutralising
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免疫動物 |
Mouse
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抗体クラス |
IgG2b
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クローン |
V1.4F5.25
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交差種 |
Mouse
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GENE ID |
50498
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Accession No.(Gene/Protein) |
NP_056581, O35228
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Gene Symbol |
EBI3
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形状 |
凍結乾燥品
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参考文献 |
Lyakh L, Trinchieri G, Provezza L, Carra G, and Gerosa F. Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans. Immunol Rev. 226: 112-131. 2008. Pflanz S., Timans J.C., Cheung J., Rosales R., Kanzler H., Gilbert J., Hibbert L., Churakova T., Travis M., Vaisberg E., Blumenschein W.M., Mattson J.D., Wagner J.L., To W., Zurawski S., McClanahan T.K., Gorman D.M., Bazan J.F., Kastelein R.A (2002). IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 16:779-790 [PubMed: 12121660] Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, and Vignali DAA. (2007) The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450 (7169): 566-9. doi:10.1038/nature06306. PMID 18033300
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[注意事項] |
濃度はロットによって異なる可能性があります。メーカーDS及びCoAからご確認ください。
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※サムネイル画像をクリックすると拡大画像が表示されます。
Neutralization: Murine CD4+CD25 (Tconv) were purified by FACS, activated with anti CD3/CD28coated beads in the presence of a titration of mouse IL 35 and 10ug/mL of 210 301 C56 antibody. Percent suppression was determined by calculating the percent decrease in counts per minute of activated Tconv plus or minus murine IL 35.
Neutralization: Human CD4+CD25- (Tconv) were purified by FACS from cord blood, activated with anti-CD3/CD28coated beads and 10IU IL-2 in the presence of human IL-35 and a titration of an isotype control or 210-301-C56 antibody. Percent neutralization was determined by calculating the percent decrease in counts per minute of activated Tconv plus (0%) or minus (100%) human IL-35 in the presence and absence of Ab.
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Neutralization: Murine CD4+CD25 (Tconv) were purified by FACS, activated with anti CD3/CD28coated beads in the presence of a titration of mouse IL 35 and 10ug/mL of 210 301 C56 antibody. Percent suppression was determined by calculating the percent decrease in counts per minute of activated Tconv plus or minus murine IL 35.
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メーカー |
品番 |
包装 |
RKL
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210-306-C56
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100 UG
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※表示価格について
当社在庫 |
なし
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納期目安 |
約10日
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保存温度 |
4℃
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