| 別品名 |
Vancomycine, Vancocin, Lyphocin, Vancor, (S(suba))-(3S,6R,7R,22R,23S,26S,36R,38aR)-44-((2-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((2R)-4-methyl-2-(methylamino)valeramido)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-
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| 別包装 |
あり
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| 純度 |
>=1050 IU/mg, bio assay
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| 分子量 |
1485.73
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| CAS RN® |
1404-93-9
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| 化合物の概要 |
Glycopeptide, binds D-Ala-D-Ala; cell wall synthesis inhibitor. 1050 IU/mg, bio assay
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| 構造 |
C66H75Cl2N9O24 HCl
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| 溶媒 |
Soluble in water. Moderately soluble in methanol. Insoluble in acetone and ether.
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| 使用目的 |
Vancomycin is a glycopeptide antibiotic originally produced by Acolatopsis orientalis. Vancomycin exhibits antibacterial activity against gram positive bacteria such as Clostridium and Staphylococcus by binding D-Ala-D-Ala and inhibiting cell wall synthesis.
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| その他 |
[融点]Decomposes when heated.
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| 参考文献 |
Allen CA, Babakhani F, Sears P, et al. Both fidaxomicin and vancomycin inhibit outgrowth of Clostridium difficile spores. Antimicrob Agents Chemother. 2013 Jan;57(1):664-7. PMID: 23147724.Chakraborty SP, Sahu SK, Pramanik P, et al. In vitro antimicrobial activity of nanoconjugated vancomycin against drug resistant Staphylococcus aureus. Int J Pharm. 2012 Oct 15;436(1-2):659-76. PMID: 22841851.Nailor MD, Sobel JD. Antibiotics for gram-positive bacterial infection: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, telavancin, and ceftaroline. Med Clin North Am. 2011 Jul;95(4):723-42, vii. PMID: 21679789.
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※表示価格について
| 当社在庫 |
なし
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| 納期目安 |
1週間程度
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| 保存温度 |
常温
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