別品名 |
Steptomycin Sesquisulfate, AgriStrep, Vetstrep
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別包装 |
あり
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純度 |
>=98%
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分子量 |
729.63
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CAS RN® |
3810-74-0
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化合物の概要 |
Aminoglycoside; protein translation inhibitor, mammalian mRNA splicing inhibitor.
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構造 |
(C21H39N7O12)2 3H2SO4
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溶媒 |
Soluble in water.
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使用目的 |
Streptomycin is an aminoglycoside originally produced by Streptomyces; it was one of the first antibiotics discovered. Streptomycin exhibits antibacterial and anti-parasitic activities, binding 16S rRNA of the 30S bacterial ribosome and inhibiting formyl-methionyl-tRNA binding; this prevents the formation of the initiation complex. Streptomycin was originally used to treat tuberculosis, but has since been used in veterinary medicine to treat gram negative bacterial infection. Streptomycin is also used as a pesticide and fungicide Streptomycin inhibits mammalian RNA splicing as well.
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その他 |
[沸点]948.2℃
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参考文献 |
Ruiz P, Rodriguez-Cano F, Zerolo FJ, et al. Streptomycin as second-line chemotherapy for tuberculosis. Rev Esp Quimioter. 2003 Jun;16(2):188-94. PMID: 12973456.Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.Zhu M, Burman WJ, Jaresko GS, et al. Population pharmacokinetics of intravenous and intramuscular streptomycin in patients with tuberculosis. Pharmacotherapy. 2001 Sep;21(9):1037-45. PMID: 11560193.
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メーカー |
品番 |
包装 |
LKT
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S7769
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25 G
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
常温
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