Glucosamine Hydrochloride  

別品名 D-Glucosamine HCl,2-Amino-2-deoxy-D-glucopyranose hydrochloride, Chitosamine hydrochloride, 2-Amino-2-deoxy-D-glucose hydrochloride
別包装 あり
純度 >=96%
分子量 215.6
CAS RN® 66-84-2
化合物の概要 Endogenous amino sugar precursor required for production of cartilage.
構造 C6H13NO5 HCl
溶媒 Soluble in water.
使用目的 Glucosamine is an endogenous amino sugar precursor to glycosylated protein and lipid formation; it is used in the making of cartilage. Glucosamine improves joint function and is often found in dietary supplements. Glucosamine exhibits anticancer and anti-fibrotic activities. In prostate cancer cells, glucosamine decreases N-glycosylation of gp130, suppressing binding of IL-6, phosphorylation of JAK2, SHP2, and STAT3, and cellular proliferation. Additionally, glucosamine decreases TGF-β1-induced expression of collagen I, fibronectin, and αSMA, inhibits phosphorylation of Smad2/3, and suppresses the development of renal fibrosis in vivo.
その他 [融点]190℃-194℃
[外観]White Crystal Powder
参考文献 Chesnokov V, Gong B, Sun C, et al. Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation. Cancer Cell Int. 2014 May 28;14:45. PMID: 24932134.Park J, Lee SY, Ooshima A, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84. PMID: 24072041.


メーカー 品番 包装
LKT G4580 100 G
希望販売価格 ¥11,000


当社在庫 なし
納期目安 1週間程度
保存温度 常温




メーカー名 LKT Laboratories, Inc.
略号 LKT