別包装 |
あり
|
純度 |
>=98%
|
分子量 |
479.61
|
CAS RN® |
14930-96-2
|
化合物の概要 |
Mycotoxin produced by Aspergillus; actin polymerization inhibitor.
|
構造 |
C29H37NO5
|
溶媒 |
DMSO or Ethanol
|
使用目的 |
Cytochalasin B is a mycotoxin actin polymerization inhibitor initially produced by species of Aspergillus. Cytochalasin B inhibits secretion of corticosterone and aldosterone from the adrenal gland in vivo. In fibroblasts, cytochalasin B inhibits FGF- and PDGF-induced mitogenesis. Additionally, this compound’s disruption of actin polymerization prevents phagocytosis in macrophages.
|
その他 |
[融点]221-223℃
|
参考文献 |
Delarue C, Esneu M, Fournier A, et al. Role of the cytoskeleton in the secretory response of the frog adrenal gland to calcitonin gene-related peptide. J Steroid Biochem Mol Biol. 1997 Sep-Oct;63(1-3):21-7. PMID: 9449202.Reist RH, Dey RD, Durham JP, et al. Inhibition of proliferative activity of pulmonary fibroblasts by tetrandrine. Toxicol Appl Pharmacol. 1993 Sep;122(1):70-6. PMID: 8104360.Painter RG, Whisenand J, McIntosh AT. Effects of cytochalasin B on actin and myosin association with particle binding sites in mouse macrophages: implications with regard to the mechanism of action of the cytochalasins. J Cell Biol. 1981 Nov;91(2 Pt 1):373-84. PMID: 7198123.
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メーカー |
品番 |
包装 |
LKT
|
C9879
|
5 MG
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
1週間程度
|
保存温度 |
4℃
|
|