別品名 |
Spectam, Spectinomycin dihydrochloride, Stanilo
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別包装 |
あり
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純度 |
>=603 μg/mg (potency)
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分子量 |
495.25
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CAS RN® |
22189-32-8
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化合物の概要 |
Aminocyclitol; protein synthesis inhibitor.
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構造 |
C14H24N2O7 2HCl 5H2O
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溶媒 |
Soluble in water to 100 mM. methanol, propylene glycol, and formamid. DMSO to 99 mg/mL, PBS to 10 mg/mL.
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使用目的 |
Spectinomycin is an aminocyclitol antibiotic initially produced by Streptomyces. Spectinomycin binds 16S rRNA of the 30S bacterial ribosome, inhibiting translocation and protein synthesis. Spectinomycin exhibits antibacterial activity and was originally used to treat gonorrhea, but has since been replaced by newer drugs.
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その他 |
[融点]205℃-207℃ (dec)
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参考文献 |
Ilina EN, Malakhova MV, Bodoev IN, et al. Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae. Front Microbiol. 2013 Jul 10;4:186. PMID: 23847609.Kehrenberg C, Schwarz S. Mutations in 16S rRNA and ribosomal protein S5 associated with high-level spectinomycin resistance in Pasteurella multocida. Antimicrob Agents Chemother. 2007 Jun;51(6):2244-6. PMID: 17371823.
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メーカー |
品番 |
包装 |
LKT
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S6018
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25 G
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
-20℃
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