別品名 |
CCRIS 3304, 4 H- 1-Benzopyran-4-one-2-(3,4-dihydroxyphenyl)- 3,5,7-trihydroxy-dihydrate
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別包装 |
あり
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純度 |
>=95%
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分子量 |
338.26
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CAS RN® |
6151-25-3
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化合物の概要 |
Flavonoid found in fruits, vegetables, and grains; RT, MAO, calcineurin inhibitor.
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構造 |
C15H10O7 2H2O
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溶媒 |
Soluble in ethanol. Insoluble in water.
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使用目的 |
Quercetin is a phytoestrogen and flavonoid found in fruits, vegetables, and grains; it exhibits antiviral, anti-inflammatory, antihypertensive, anti-allergic, immunomodulatory, and neuromodulatory activities. Quercetin inhibits reverse transcriptase activity and suppresses replication of hepatitis C virus. In vivo, quercetin increases energy expenditure and decreases release of inflammatory cytokines. Clinically, this compound decreases blood pressure. In animal models of OVA-induced allergy, quercetin decreases levels of IL-4 and Th2 cytokines and increases levels of IFN-γ and Th1 cytokines. Quercetin also inhibits calcineurin and monoamine oxidase (MAO).
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その他 |
[融点]314℃(dec) [外観]Yellow or greenish yellow crystalline powder
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参考文献 |
Pisonero-Vaquero S, Garcia-Mediavilla MV, Jorquera F, et al. Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin. Lab Invest. 2014 Mar;94(3):262-74. PMID: 24492281.Park HJ, Lee CM, Jung ID, et al. Quercetin regulates Th1/Th2 balance in a murine model of asthma. Int Immunopharmacol. 2009 Mar;9(3):261-7. PMID: 19061976.Saaby L, Rasmussen HB, Jager AK. MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull. J Ethnopharmacol. 2009 Jan 12;121(1):178-81. PMID: 19013512.Stewart LK, Soileau JL, Ribnicky D, et al. Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Metabolism. 2008 Jul;57(7 Suppl 1):S39-46. PMID: 18555853.Edwards RL, Lyon T, Litwin SE, et al. Quercetin reduces blood pressure in hypertensive subjects. J Nutr. 2007 Nov;137(11):2405-11. PMID: 17951477.Spedding G, Ratty A, Middleton E Jr. Inhibition of reverse transcriptases by flavonoids. Antiviral Res. 1989 Sep;12(2):99-110. PMID: 2480745.
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メーカー |
品番 |
包装 |
LKT
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Q8016
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500 G
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
4℃
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