別包装 |
あり
|
純度 |
>=98%
|
分子量 |
1079.27
|
CAS RN® |
68406-26-8
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化合物の概要 |
Triterpene saponin found in species of Panax.
|
構造 |
C53H90O22
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使用目的 |
Ginsenoside Rb3 is a triterpene saponin originally found in species of Panax (ginseng) that exhibits cardioprotective, antioxidative, antidepressant, and anti-diabetic activities. Ginsenoside Rb3 inhibits contractions in aortic rings and suppresses expression of ROS, NOX-2, and NOX-4, decreasing oxidative stress and improving endothelial function. In diabetic mice, ginsenoside Rb3 decreases blood glucose levels and improves oral glucose tolerance. Ginsenoside Rb3 also decreases immobility time in the forced swim, tail suspension, and learned helplessness tests. Additionally, this compound decreases levels of malondialdehyde and increases activity of superoxide dismutase, decreasing infarct size in animal models of myocardial ischemia/reperfusion.
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その他 |
[外観]White Powder
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参考文献 |
Wang Y, Dong J, Liu P, et al. Ginsenoside Rb3 attenuates oxidative stress and preserves endothelial function in renal arteries from hypertensive rats. Br J Pharmacol. 2014 Jul;171(13):3171-81. PMID: 24571453.Bu QT, Zhang WY, Chen QC, et al. Anti-diabetic effect of ginsenoside Rb(3) in alloxan-induced diabetic mice. Med Chem. 2012 Sep;8(5):934-41. PMID: 22741793.Cui J, Jiang L, Xiang H. Ginsenoside Rb3 exerts antidepressant-like effects in several animal models. J Psychopharmacol. 2012 May;26(5):697-713. PMID: 21948936.Shi Y, Han B, Yu X, et al. Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats. Pharm Biol. 2011 Sep;49(9):900-6. PMID: 21591990.
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メーカー |
品番 |
包装 |
LKT
|
G3554
|
25 MG
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※表示価格について
当社在庫 |
なし
|
納期目安 |
1週間程度
|
保存温度 |
4℃
|
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