別包装 |
あり
|
純度 |
>=98%
|
分子量 |
785.01
|
CAS RN® |
52286-74-5
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化合物の概要 |
Triterpene saponin found in species of Panax.
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構造 |
C42H72O13
|
使用目的 |
Ginsenoside Rg2 is a triterpene saponin originally found in species of Panax that exhibits anti-atherosclerotic, anti-diabetic, and neuroprotective activities. Ginsenoside Rg2 inhibits LPS-stimulated production of VCAM-1 and ICAM-1, prevents degradation of IκBα, and suppresses leukocyte adhesion in models of atherosclerosis. Ginsenoside Rg2 also decreases production of PEPCK and G6Pase and phosphorylates AMPK and GSK-3β, suppressing hepatic glucose production in vitro. Additionally, this compound decreases expression of Bcl-2 and HSP70 and increases expression of Bax and p53, improving neural performance and cognition in animal models of vascular dementia.
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その他 |
[外観]White powder[沸点]889.6℃
|
参考文献 |
Cho YS, Kim CH, Ha TS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013 Apr;17(2):133-7. PMID: 23626475.Yuan HD, Kim do Y, Quan HY, et al. Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cells. Chem Biol Interact. 2012 Jan 5;195(1):35-42. PMID: 22062806.Zhang G, Liu A, Zhou Y, et al. Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia. J Ethnopharmacol. 2008 Feb 12;115(3):441-8. PMID: 18083315.
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メーカー |
品番 |
包装 |
LKT
|
G3459
|
10 MG
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※表示価格について
当社在庫 |
なし
|
納期目安 |
1週間程度
|
保存温度 |
4℃
|
|