Anti Ubiquitin-Conjugating Enzyme E2 J2 (Ube2j2)  

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別品名 Ubiquitin-conjugating enzyme E2 J2 Non-canonical ubiquitin-conjugating enzyme 2 Ube2j2
種由来 Human
標識物 Unlabeled
精製度 Affinity Purified
適用 Western Blot
Enzyme Linked Immunosorbent Assay
免疫動物 Rabbit
交差種 Human
GENE ID 118424
Accession No.(Gene/Protein) 251757431, Q8N2K1
Gene Symbol UBE2J2
形状 滅菌済み液状品
その他 [Uniprot ID]Q8N2K1
参考文献 Lenk,U., Yu,H., Walter,J., Gelman,M.S., Hartmann,E., Kopito,R.R. and Sommer,T. (2002) A role for mammalian Ubc6 homologues in ER-associated protein degradation. J. Cell Sci. 115:3007-3014. Lester,D., Farquharson,C., Russell,G. and Houston,B. (2000) Identification of a family of noncanonical ubiquitin-conjugating enzymes structurally related to yeast UBC6. Biochem. Biophys. Res. Commun. 269(2):474-480. Jentsch, S. and Pyrowolakis, G. (2000) Ubiquitin and its kin: how close are the family ties? Trends Cell Biol. 10(8):335-342.


Most modifiers mature by proteolytic processing from inactive precursors (''a'' = amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thioesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein)/CBC(cullin-2/elonginB/elonginC)-like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked head-to-tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. (From Jentsch & Pyrowolakis (2000); see references below.)

メーカー 品番 包装
RKL 600-401-B43 100 UG
[0.91 mg/mL]
希望販売価格 ¥88,000


当社在庫 なし
納期目安 約10日
保存温度 -20℃




メーカー名 Rockland Immunochemicals, Inc.
略号 RKL