| 別品名 |
Non-canonical ubiquitin-conjugating enzyme 1, Yeast ubiquitin-conjugating enzyme UBC6 homolog E
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| 抗原部位 |
N-terminus
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| 種由来 |
Human
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| 標識物 |
Unlabeled
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| 精製度 |
Affinity Purified
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| 適用 |
Western Blot
Enzyme Linked Immunosorbent Assay
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| 免疫動物 |
Rabbit
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| 交差種 |
Human
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| GENE ID |
51465
|
| Accession No.(Gene/Protein) |
Q9Y385
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| Gene Symbol |
UBE2J1
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| 形状 |
滅菌済み液状品
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| 参考文献 |
[Pub Med ID]20682309
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| [注意事項] |
濃度はロットによって異なる可能性があります。メーカーDS及びCoAからご確認ください。
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※サムネイル画像をクリックすると拡大画像が表示されます。
Most modifiers mature by proteolytic processing from inactive precursors (a = amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thioesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin 1/F box protein)/CBC(cullin 2/elonginB/elonginC) like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked head to tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. (From Jentsch & Pyrowolakis (2); see references below.)
Western blot using Rockland's affinity purified anti-Ube2j1 antibody shows detection of Ube2j1 in 293 cells over-expressing Myc-Ube2j1 (Lane 2). Lane 1 contains lysate from mock-transfected 293 cells. Personal Communication, A. Weissman & T. Shang, CCR-NCI, Frederick, MD
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Most modifiers mature by proteolytic processing from inactive precursors (a = amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thioesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin 1/F box protein)/CBC(cullin 2/elonginB/elonginC) like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked head to tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. (From Jentsch & Pyrowolakis (2); see references below.)
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| メーカー |
品番 |
包装 |
|
RKL
|
600-401-991S
|
25 UL
|
※表示価格について
| 当社在庫 |
なし
|
| 納期目安 |
約10日
|
| 保存温度 |
-２０℃
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