| 別品名 |
AT mutated antibody, AT protein antibody, AT1 antibody, ATA antibody, Ataxia telangiectasia gene mutated in human beings antibody, Ataxia telangiectasia mutated antibody, ATC antibody
|
| 種由来 |
Human
|
| 標識物 |
Unlabeled
|
| 精製度 |
Affinity Purified
|
| 適用 |
Western Blot
Enzyme Linked Immunosorbent Assay
|
| 免疫動物 |
Sheep
|
| 交差種 |
Human
|
| 翻訳後修飾 |
リン酸化
|
| GENE ID |
472
|
| Accession No.(Gene/Protein) |
NP_000042, Q13315
|
| Gene Symbol |
ATM
|
| 形状 |
滅菌済み液状品
|
| 参考文献 |
Bakkenist, C. J. & Kastan, M. B. (2003). DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421, 499-506. Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB. (2004) Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev. 18(12):1423-38. Falck, J. Coates, J. and Jackson, S.P. (2005) Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 434: 605-611.
|
| [注意事項] |
濃度はロットによって異なる可能性があります。メーカーDS及びCoAからご確認ください。
|
|
※サムネイル画像をクリックすると拡大画像が表示されます。
Schematic of ATM induction by DNA damage.
Western Blot of Sheep Anti-ATM pS1981 polyclonal antibody. Lane 1: untreated MCF-7 cell lysate (p/n W09-000-360). Lane 2: Hydrogen Peroxide stimulated MCF-7 Whole Cell Lysate (p/n W09-000-366). Load: 35 ug per lane. Primary antibody: ATM pS1981 antibody at 1:1000 for 1 h at room temperature. Secondary antibody: IRDyeTM800 conjugated Donkey anti-Sheep IgG secondary antibody at 1:5,000 for 1h at room temperature. Block: 5% BLOTTO (B501) overnight at 4C. Predicted/Observed size: 370 kDa, ATM (370 kDa) is indicated by an arrow. Other band(s): ATM splice variants and isoforms.
|
|
|
|
Schematic of ATM induction by DNA damage.
|
|
|
| メーカー |
品番 |
包装 |
|
RKL
|
600-601-400
|
100 UG
|
※表示価格について
| 当社在庫 |
なし
|
| 納期目安 |
約10日
|
| 保存温度 |
-２０℃
|
|
