肝細胞 (HH)  

別品名 HH
種由来 Human
由来詳細 肝臓
その他 [その他]推奨培地品番#5201
参考文献 1.) Soronen, J., YkiJrvinen, H., Zhou, Y., Sdevirta, S., Sarin, A., Leivonen, M., Sevastianova, K., Perttil, J., Laurila, P., Sigruener, A., Schmitz, G. & Olkkonen, V.M. (2016) Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease Physiol Rep. 4
2.) Harmon, B., Bird, S.W., Schudel, B.R., Hatch, A.V., Rasley, A. & Negrete, O.A.(2016) 'A GenomeWide RNA Interference Screen Identifies a Role for Wnt/?Catenin Signaling during Rift Valley Fever Virus Infection' J Virol. VOL 90
3.) Yuan, J., Li, W., Huang, J., Guo, X., Li, X., Lu, X., Huang, X. & Zhang, H. (2015) Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane Stem Cell Res Ther. 6
4.) Xiao, H., Bid, H.K., Jou, D., Wu, X., Yu, W., Li, C., Houghton, P.J. & Lin, J. (2015) A Novel Small Molecular STAT3 Inhibitor, LY5, Inhibits Cell Viability, Cell Migration, and Angiogenesis in Medulloblastoma Cells* J Biol Chem. 290
5.) Li, J., Zhou, J., Zhang, D., Song, Y., She, J. & Bai, C. (2015) Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury J Cell Mol Med. 19
6.) Kong, L., Li, S., Huang, M., Xiong, Y., Zhang, Q., Ye, L., Liu, J., Zhu, X., Sun, R. & Guo, Y. (2015) The Roles of Endoplasmic Reticulum Overload Response Induced by HCV and NS4B Protein in Human Hepatocyte Viability and Virus Replication PLoS One. 10
7.) Feng, Y.M., Feng, C.W., Chen, S.Y., Hsieh, H.Y., Chen, Y.H. & Hsu, C.D. (2015) Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase BMC Cancer. 15
8.) Chiang TS, Yang KC, Chiou LL, Huang GT, Lee HS.(2014) "Enhancement of CYP3A4 Activity in Hep G2 Cells by Lentiviral Transfection of Hepatocyte Nuclear Factor-1 Alpha." PloS one. 9: e94885.
9.) Liu Y, Liu A, Xu Z, Yu W, Wang H, Li C, Lin J. (2011) "XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells." Apoptosis. 16: 502-10.
10.) Braconi C, Valeri N, Gasparini P, Huang N, Taccioli C, Nuovo G, Suzuki T, Croce CM, Patel T. (2010) "Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes." Clin Cancer Res. 16: 957-66.
11.) Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N. (2010) "The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib." Hepatology. 52: 1310-21.
12.) Liu Y, Li PK, Li C, Lin J. (2010) "Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells." J Biol Chem. 285: 27429-39.
13.) Shen Q, Cicinnati VR, Zhang X, Iacob S, Weber F, Sotiropoulos GC, Radtke A,Lu M, Paul A, Gerken G, Beckebaum S. (2010) "Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion." Mol Cancer. 9: 227.
14.) Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, Tatsumi T,Ishida H, Noda T, Nagano H, Doki Y, Mori M, Hayashi N. (2010) "The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma." J Hepatol. 52: 698-704.
15.) Yeon JH, Na D,Park JK. (2010) "Hepatotoxicity assay using human hepatocytes trapped in microholes of a microfluidic device." Electrophoresis. 31: 3167-74.
16.) Braconi C, Meng F, Swenson E, Khrapenko L, Huang N, Patel T. (2009) "Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures." Cancer. 115: 3738-48.
[注意事項] ScienCell Research Laboratories社では、推奨の培地及び試薬を用いて、推奨プロトコルに従い培養された場合のみ品質を保証しております。


Human Hepatocytes

メーカー 品番 包装
SCR 5200 1 VIAL
[1 x 10^6 cells/vial]
希望販売価格 ¥196,000


当社在庫 なし
納期目安 約10日
保存温度 液体窒素




メーカー名 ScienCell Research Laboratories
略号 SCR