別品名 |
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol; 11-Deoxojervine; (3β,23β)-17,23-Epoxyveratraman-3-ol;11-Deoxyjervine;
|
分子量 |
411.62
|
CAS RN® |
4449-51-8
|
構造 |
C27H41NO2
|
溶媒 |
Chloroform (Slightly), Methanol (Slightly)
|
使用目的 |
Cyclopamine antibacterial properties. Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched. Potent Hedgehog inhibitor.Solubility: 1mg of Cyclopamine dissolves in 0.2ml DMSO with heating to approximately 70 degrees (ca. 12 mmol sol.)Solubility: 4mg of Cyclopamine dissolves in 1ml 95% Ethanol
|
その他 |
[融点]>227℃ (dec.) [性状]White to Off-White Solid
|
参考文献 |
Kanda, S., et al.: J. Biol. Chem., 278,10, 8244 (2003), Rao, et al.: Development, 130, 1549 (2003), Taipale, J., et al. Nature 406, 1005 (2000), Perron, M., et al. Development 130, 1565 (2003), Watkins, D.N., et al.: Nature, 422, 313 (2003)
|
※サムネイル画像をクリックすると拡大画像が表示されます。
|
|
|
メーカー |
品番 |
包装 |
TRC
|
C988400
|
1 MG
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
2週間程度
|
保存温度 |
-20℃
|
|