| 別品名 |
Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b
|
| 抗原部位 |
C-terminus
|
| 種由来 |
Rat
|
| 精製度 |
Affinity Purified
|
| 適用 |
Western Blot
|
| 免疫動物 |
Rabbit
|
| 交差種 |
Human
Rat
|
| GENE ID |
Grin2b
|
| Accession No.(Gene/Protein) |
Q00960
|
| Gene Symbol |
24410
|
| 分子量 |
166071
|
| 参考文献 |
Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD (2003) Tyrosinedephosphorylation and ethanol inhibition of N-methyl-D-aspartate receptor function. J Biol Chem 278:11020-11025.Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission andplasticity. Trends Neurosci 25:571-577.Clayton DA, Grosshans DR, Browning MD (2002a) Aging and surface expression of hippocampal NMDA receptors. JBiol Chem 277:14367-14369.Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD (2002b) A hippocampal NR2B deficit can mimicage-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 22:3628-3637.Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA butnot AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33.Lovinger DM, White G, Weight FF (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons.Science 243:1721-1724.Lu W-Y, Xiong Z-G, Lei S, Orser BA, Browning MD, MacDonald JF (1999) G-protein coupled receptors act via proteinkinase C and Src to regulate NMDA receptors. Nature Neurosci 2:331-338.Snell LD, Nunley KR, Lickteig RL, Browning MD, Tabakoff B, Hoffman PL (1996) Regional and subunit specificchanges in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion. MolBrain Res 40:71-78.Wenthold RJ, Prybylowski K, Standley S, Sans N, Petralia RS (2003) Trafficking of NMDA receptors. Annu RevPharmacol Toxicol 43:335-358.Pradeep Kurup, Yongfang Zhang, Jian Xu, Deepa V. Venkitaramani, Vahram Haroutunian, Paul Greengard, AngusC. Nairn, and Paul J. Lombroso (2010) Aβ-Mediated NMDA Receptor Endocytosis in Alzheimer's DiseaseInvolves Ubiquitination of the Tyrosine Phosphatase STEP61. J. Neurosci., 30: 5948 - 5957.Jian Xu, Pradeep Kurup, Yongfang Zhang, Susan M. Goebel-Goody, Peter H. Wu, Ammar H. Hawasli, Matthew L.Baum, James A. Bibb, and Paul J. Lombroso Extrasynaptic NMDA Receptors Couple Preferentially toExcitotoxicity via Calpain-Mediated Cleavage of STEP (2009) J. Neurosci., 29: 9330 - 9343.Kurtis D. Davies, Susan M. Goebel-Goody, Steven J. Coultrap, and Michael D. Browning (2008) Long Term SynapticDepression That Is Associated with GluR1 Dephosphorylation but Not -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Internalization J. Biol. Chem., 283: 33138 - 33146.Erin H. Norris and Sidney Strickland (2007) Modulation of NR2B-regulated contextual fear in the hippocampus by thetissue plasminogen activator system. PNAS, 104: 13473 - 1347.Tatyana Chernova, Joern R. Steinert, Christopher J. Guerin, Pierluigi Nicotera, Ian D. Forsythe, and Andrew G. Smith(2007) Neurite Degeneration Induced by Heme Deficiency Mediated via Inhibition of NMDA Receptor-DependentExtracellular Signal-Regulated Kinase 1/2 Activation J. Neurosci., 27: 8475 - 8485.Tianna R. Hicklin, Peter H. Wu, Richard A. Radcliffe, Ronald K. Freund, Susan M. Goebel-Goody, Paulo R. Correa,William R. Proctor, Paul J. Lombroso, and Michael D. Browning (2011) Alcohol inhibition of the NMDA receptorfunction, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase PNAS,Apr 2011; 108: 6650 - 6655.
|
|
※サムネイル画像をクリックすると拡大画像が表示されます。
|
|
|
|
| メーカー |
品番 |
包装 |
|
ABH
|
AN1232
|
100 UL
|
※表示価格について
| 当社在庫 |
なし
|
| 納期目安 |
3週間程度
|
| 保存温度 |
-２０℃
|
|
