別品名 |
Complement C5, Hemolytic complement, Gene name: C5
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種由来 |
Mouse
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標識物 |
Unlabeled
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適用 |
IHC paraffin embedding section IHC frozen section Immuno Fluorescence Immuno Assay Immunoprecipitation Functional Assay
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免疫動物 |
Mouse
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抗体クラス |
IgG1
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クローン |
BB5.1
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交差種 |
Rat
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添加剤 |
BSA free, low endotoxin
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形状 |
溶液
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使用目的 |
Effective inhibitor of C5 activation
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参考文献 |
1. Frei, Y et al; Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-C5 antibodies. Mol Cell Probes 1987, 1: 141 2. Thurman, J et al; C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ischemia/reperfusion. J Immunol 2007, 178: 1819 3. Mihai, S et al; The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita. J Immunol 2007, 178: 6514 4. Wang, H et al; Inhibition of terminal complement components in presensitized transplant recipients prevents antibody-mediated rejection leading to long-term graft survival and accommodation. J Immunol 2007, 179: 4451 5. Huugen, D et al; Inhibition of complement factor C5 protects against antimyeloperoxidase antibody-mediated glomerulonephritis in mice. Kidney Int 2007, 71: 646 6. Nilsson, K et al. Enhanced susceptibility to low-dose collagen-induced arthritis in CR1/2-deficient female mice ?“ possible role of estrogen on CR1 expression. Faseb 2009, 23: 2450 7. Copland, D et al. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clin exp immunol 2010, 159:303 8. Pavlovski, D et al; Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis, Faseb 2012, 26: 3680
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[注意事項] |
ラットとの交差反応性はIHCでのみテストされており、他のアプリケーションではテストされていません。
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メーカー |
品番 |
包装 |
HCB
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HM1073-1MG
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1 MG
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※表示価格について
当社在庫 |
なし
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納期目安 |
2週間程度
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保存温度 |
4℃
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