種由来 |
Human
|
適用 |
Western Blot IHC paraffin embedding section Immuno Fluorescence Immuno Assay Immunoprecipitation
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免疫動物 |
Mouse
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抗体クラス |
IgG1
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クローン |
2C1
|
形状 |
溶液
|
参考文献 |
1. Miranda, E et al; A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency. Hepatology 2010, 52: 1078. 2. Ekeowa, U et al; Defining the mechanism of polymerization in the serpinopathies. PNAS 2010, 107: 17146. 3. Morris, H et al; ANCA-associated vasculitis is linked to carriage of the Z allele of I±1 antitrypsin and its polymers. Ann Rheum Dis 2011, 70: 1851. 4. Yamasaki, M et al; Molecular basis of I±1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer. EMBO reports 2011, 12: 1011. 5. Ordonez, A et al; A single-chain variable fragment intrabody prevents intracellular polymerization of Z a1-antitrypsin while allowing its antiproteinase activity. FASEB Journal 2015, 29: 2667 6. Tan, L et al; Characterising the association of latency with I±1-antitrypsin polymerisation using a novel monoclonal antibody. Int J Bio & Cell Biol 2015, 58: 81 7. Dickens, J et al; The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-a1-antitrypsin. FASEB Journal 2016, 30: 4083 8. Haq, I et al; Deficiency Mutations of Alpha-1 Antitrypsin. Am J Respir Cell Mol Biol 2016, 1: 71 9. Khodayari, N et al; Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation. J Cell Bio 2017, 118: 3090 10. Miranda, E et al; The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization. FEBS Journal 2017, 284: 2110
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メーカー |
品番 |
包装 |
HCB
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HM2289-500UG
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500 UG
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※表示価格について
当社在庫 |
なし
|
納期目安 |
2週間程度
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保存温度 |
4℃
|
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