別品名 |
LY294002 HCl
|
別包装 |
あり
|
純度 |
>=98%
|
分子量 |
343.81
|
CAS RN® |
934389-88-5
|
化合物の概要 |
Inhibitor of PI3K.
|
参考文献 |
Avni D, Glucksam Y, Zor T. The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 modulates cytokine expression in macrophages via p50 nuclear factor κB inhibition, in a PI3K-independent mechanism. Biochem Pharmacol. 2012 Jan 1;83(1):106-14. PMID: 22005520. Salh B, Wagey R, Marotta A, et al. Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production. J Immunol. 1998 Dec 15;161(12):6947-54. PMID: 9862729. Nakamura I, Sasaki T, Tanaka S, et al. Phosphatidylinositol-3 kinase is involved in ruffled border formation in osteoclasts. J Cell Physiol. 1997 Aug;172(2):230-9. PMID: 9258344. Rosenzweig KE, Youmell MB, Palayoor ST, et al. Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay. Clin Cancer Res. 1997 Jul;3(7):1149-56. PMID: 9815794.
|
|
メーカー |
品番 |
包装 |
LKT
|
L960002
|
5 MG
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
1週間程度
|
保存温度 |
常温
|
|