Anti SMAD4  

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別品名 Deletion target in pancreatic carcinoma 4 antibody, DPC 4 antibody, MAD mothers against decapentaplegic homolog 4 antibody, MADH 4 antibody
抗原部位 C-terminus
種由来 Human
標識物 Unlabeled
精製度 Affinity Purified
適用 Western Blot
Enzyme Linked Immunosorbent Assay
免疫動物 Rabbit
交差種 Human
GENE ID 4089
Accession No.(Gene/Protein) 13603414, Q13485
Gene Symbol SMAD4
形状 滅菌済み液状品
その他 [Uniprot ID]Q13485
参考文献 Karlsson,G., Blank,U., Moody,J.L., Ehinger,M., Singbrant,S., Deng,C.X. and Karlsson,S. (2007) Smad4 is critical for self-renewal of hematopoietic stem cells. J. Exp. Med. 204 (3), 467-474. Wang,L.H., Kim,S.H., Lee,J.H., Choi,Y.L., Kim,Y.C., Park,T.S., Hong,Y.C., Wu,C.F. and Shin,Y.K. (2007) Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression. Clin. Cancer Res. 13 (1), 102-110. Lim,S.K. and Hoffmann,F.M. (2006) Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling. Proc. Natl. Acad. Sci. U.S.A. 103 (49), 18580-18585. Liang,M., Melchior,F., Feng,X.H. and Lin,X. (2004) Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1. J. Biol. Chem. 279 (22), 22857-22865. Roelen,B.A., Cohen,O.S., Raychowdhury,M.K., Chadee,D.N., Zhang,Y., Kyriakis,J.M., Alessandrini,A.A. and Lin,H.Y. (2003) Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. Am. J. Physiol., Cell Physiol. 285 (4), C823-C830.


Western blot using Rockland's affinity purified anti-SMAD4 to detect over-expressed SMAD4 in transfected COS cells (lane 2). Lane 1 contains lysate from mock transfected COS cells. A doublet band is seen in the SMAD4 transfected lysate with the upper band (arrowhead) representing SMAD4 and the lower band being non-specific staining. The membrane was probed with the primary antibody at a 1:1,000 dilution. Personal Communication Kathleen Flanders, CCR-NCI, Bethesda, MD.

メーカー 品番 包装
RKL 600-401-A41 100 UG
[1.2 mg/mL]
希望販売価格 ¥89,000


当社在庫 なし
納期目安 約10日
保存温度 -20℃




メーカー名 Rockland Immunochemicals, Inc.
略号 RKL