| 別品名 |
Deletion target in pancreatic carcinoma 4 antibody, DPC 4 antibody, MAD mothers against decapentaplegic homolog 4 antibody, MADH 4 antibody
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| 抗原部位 |
C-terminus
|
| 種由来 |
Human
|
| 標識物 |
Unlabeled
|
| 精製度 |
Affinity Purified
|
| 適用 |
Western Blot
Enzyme Linked Immunosorbent Assay
|
| 免疫動物 |
Rabbit
|
| 交差種 |
Human
Mouse
Xenopus
|
| GENE ID |
4089
|
| Accession No.(Gene/Protein) |
Q13485
|
| Gene Symbol |
SMAD4
|
| 形状 |
滅菌済み液状品
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| 参考文献 |
Karlsson,G., Blank,U., Moody,J.L., Ehinger,M., Singbrant,S., Deng,C.X. and Karlsson,S. (2007) Smad4 is critical for self-renewal of hematopoietic stem cells. J. Exp. Med. 204 (3), 467-474. Wang,L.H., Kim,S.H., Lee,J.H., Choi,Y.L., Kim,Y.C., Park,T.S., Hong,Y.C., Wu,C.F. and Shin,Y.K. (2007) Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression. Clin. Cancer Res. 13 (1), 102-110. Lim,S.K. and Hoffmann,F.M. (2006) Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling. Proc. Natl. Acad. Sci. U.S.A. 103 (49), 18580-18585. Liang,M., Melchior,F., Feng,X.H. and Lin,X. (2004) Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1. J. Biol. Chem. 279 (22), 22857-22865. Roelen,B.A., Cohen,O.S., Raychowdhury,M.K., Chadee,D.N., Zhang,Y., Kyriakis,J.M., Alessandrini,A.A. and Lin,H.Y. (2003) Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. Am. J. Physiol., Cell Physiol. 285 (4), C823-C830.
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| [注意事項] |
濃度はロットによって異なる可能性があります。メーカーDS及びCoAからご確認ください。
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※サムネイル画像をクリックすると拡大画像が表示されます。
Western blot using Rockland's affinity purified anti-SMAD4 to detect over-expressed SMAD4 in transfected COS cells (lane 2). Lane 1 contains lysate from mock transfected COS cells. A doublet band is seen in the SMAD4 transfected lysate with the upper band (arrowhead) representing SMAD4 and the lower band being non-specific staining. The membrane was probed with the primary antibody at a 1:1,000 dilution. Personal Communication Kathleen Flanders, CCR-NCI, Bethesda, MD.
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Western blot using Rockland's affinity purified anti-SMAD4 to detect over-expressed SMAD4 in transfected COS cells (lane 2). Lane 1 contains lysate from mock transfected COS cells. A doublet band is seen in the SMAD4 transfected lysate with the upper band (arrowhead) representing SMAD4 and the lower band being non-specific staining. The membrane was probed with the primary antibody at a 1:1,000 dilution. Personal Communication Kathleen Flanders, CCR-NCI, Bethesda, MD.
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| メーカー |
品番 |
包装 |
|
RKL
|
600-401-A41
|
100 UG
|
※表示価格について
| 当社在庫 |
なし
|
| 納期目安 |
約10日
|
| 保存温度 |
-２０℃
|
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