| 別品名 |
DKFZp781A0353 antibody, Human phosphatidylinositol 3 kinase homolog antibody, MGC74674 antibody, Serine protein kinase ATM antibody, T cell prolymphocytic leukemia antibody
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| 抗原部位 |
a.a.1974-1988
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| 種由来 |
Human
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| 標識物 |
Unlabeled
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| 精製度 |
Ig fraction - Protein A
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| 適用 |
Enzyme Linked Immunosorbent Assay
Immunohistochemistry
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| 免疫動物 |
Mouse
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| 抗体クラス |
IgG2a
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| クローン |
7C10D8
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| 交差種 |
Human
Mouse
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| 翻訳後修飾 |
リン酸化
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| GENE ID |
472
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| Accession No.(Gene/Protein) |
NP_000042, Q13315
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| Gene Symbol |
ATM
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| 形状 |
滅菌済み液状品
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| 参考文献 |
[Pub Med ID]23754744, 24914237, 25253740, 25568088, 28432589, 30931986, 23897887, 15175241, 15846060, 18641004, 19091442, 19234633, 19884805, 20038817, 20404006, 22532587, 23063797, 24583641, 24987917, 25498542+他多数
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| [注意事項] |
濃度はロットによって異なる可能性があります。メーカーDS及びCoAからご確認ください。
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※サムネイル画像をクリックすると拡大画像が表示されます。
Determination of ATM and ATMp antibodies specificity by western blotting. Western blot analysis of neuroretinas and brains from adult Atm deficient and adult C57BL/6J mice was performed with monoclonal antibodies raised against ATM and ATMp, and with polyclonal antibody B actin (internal control). Specific bands for ATM (350？kDa), ATMp (350？kDa), and B actin (35？kDa) were detected by western blot analysis of protein homogenates extracted from different mouse tissues (neuroretina and brain). No band could be detected in protein homogenates from Atm deficient mice tissues blotted with either specific ATM or specific ATMp antibody. Figure provided by CiteAb. Source: Mol Vis, PMID: 19234633.
ATM authophosphorylation.
Anti ATM monoclonal Antibody was used to show constitutive activation of the ATM pathway in human urinary bladder cancer. Anti-ATM Protein Kinase pS1981 (clone # 7C10D8 ) was used to stain normal uroepithelium, early superficial lesions (Ta), and earliest invasive (T1) primary carcinomas. ATM protein is ubiquitously expressed, but Ser 1981-phosphorylated ATM (pS-ATM) is detectable only in tumor tissues. See Bartkova et al. for additional details. Reprinted by permission from Nature (Cell Cycle 4;(6), 2005) Macmillan Publishers Ltd.
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Determination of ATM and ATMp antibodies specificity by western blotting. Western blot analysis of neuroretinas and brains from adult Atm deficient and adult C57BL/6J mice was performed with monoclonal antibodies raised against ATM and ATMp, and with polyclonal antibody B actin (internal control). Specific bands for ATM (350？kDa), ATMp (350？kDa), and B actin (35？kDa) were detected by western blot analysis of protein homogenates extracted from different mouse tissues (neuroretina and brain). No band could be detected in protein homogenates from Atm deficient mice tissues blotted with either specific ATM or specific ATMp antibody. Figure provided by CiteAb. Source: Mol Vis, PMID: 19234633.
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| メーカー |
品番 |
包装 |
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RKL
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200-301-500
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100 UG
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※表示価格について
| 当社在庫 |
なし
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| 納期目安 |
約10日
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| 保存温度 |
-２０℃
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