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| 種由来 |
Human
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| 由来詳細 |
placenta
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| 交差種 |
Human
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| 適用 |
Western Blot Immuno Blot IHC paraffin embedding section Immuno Fluorescence Enzyme Linked Immunosorbent Assay Radio Immunoassay
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| 免疫動物 |
Rabbit
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| 標識物 |
Unlabeled
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| 精製度 |
Affinity Purified
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| 概要 |
Type IV collagen is a sheet-forming type of collagen found in basement membranes where it serves a critical scaffolding function. In mammals, six proteins make up the type IV collagen family with the distribution of family members being tissue-specific. Structurally, three collagen IV alpha chains assemble to form a flexible heterotrimeric protomer that can self-assemble into network polymers.?Tissue injury in the autoimmune disease Goodpasture syndrome is due to pathogenic autoantibodies targeting the Collagen IV α3 chain. Mutations in COL4A5 are associated with Alport syndrome. [according to RefSeq]
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| 使用文献 |
≪Storage and qualification of viable intact human amniotic graft and technology transfer to a tissue bank. Cell Tissue Bank. 2014 Jun;15(2):267-75.≫Laurent R., Nallet A., Obert L., Nicod L., Gindraux F. ≪Glomerular expression of type IV collagen chains in normal and X-linked alport syndrome kidneys. Am. J. Pathol 2000, 156, 1901-1910.≫Heidet L., Cai Y., Guicharnaud L., Antignac C., Gubler M.C. ≪Serum laminin and type IV collagen are accurate markers of histologically severe alcoholic hepatitis in patients with cirrhosis. J. Hepatol. 2000, 32, 412-418.≫Castera L., Hartmann D.J., Chapel F., Guettier C., Mal F., Lons T., Richardet J.P., Grimbert S., Morassi O., Beaugrand M., Trinchet J.C. ≪Spatiotemporal patterns of expression of extracellular matrix molecules in the developing and adult rat olfactory system. Neuroscience 1998, 84, 1135-1150.≫Julliard A.K., Hartmann D.J. ≪Lysyl oxidase gene expression in the stromal reaction to in situ and invasive ductal breast carcinoma. Am. J. Pathol. 1997, 150, 497-507.≫Peyrol S., Raccurt M., Gerard F., Gleyzal C., Grimaud J.A., Sommer P. ≪Collagen distribution in focal and segmental glomerulosclerosis: an immunofluorescence and ultrastructural immunogold study. J. Pathol. 1996, 179, 188-196.≫Cai Y., Sich M., Beziau A., Kleppel M.M., Gubler M.C. ≪Fibrosing vasculitis in Wegener's granulomatosis : ultrastructural and immunohistochemical analysis of the vascular lesions. Virchows Arch. 1995, 427, 385-393.≫Gindre D., Peyrol S., Raccurt M., Sommer P., Loire. R., Grimaud J.A., Cordier J.F. ≪Imbalance between 95 kDa type IV collagenase and tissue inhibitor of metalloproteinases in sputum of patients with cystic fibrosis. Am J Respir Crit Care Med 1995, 152, 765-774.≫Delacourt C., Le Bourgeois M., D'Ortho M.P., Doit C., Scheinmann P., Navarro J., Harf A., Hartmann D.J., Lafuma C. その他
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| メーカー |
品番 |
包装 |
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NOT
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20411-1
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0.1 ML
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※表示価格について
| 当社在庫 |
なし
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| 納期目安 |
3週間程度
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| 保存温度 |
-20℃
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