別品名 |
Neocnidilide, 3-Butyl-3α,4,5,6-tetrahydro-1(3H)-isobenzofuranone
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別包装 |
あり
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純度 |
>=98%
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分子量 |
194.13
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CAS RN® |
6415-59-4
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化合物の概要 |
Phthalide found in celery seeds; COX-1, COX-2, topoisomerase I, topoisomerase II inhibitor.
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構造 |
C12H18O2
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溶媒 |
Soluble in acetonitrile, ethanol, and methanol.
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使用目的 |
Sedanolide is a phthalide found in celery seeds that exhibits anti-inflammatory, antifungal, anti-parasitic, and nematocidal activities. Sedanolide inhibits COX-1 and COX-2 as well as topoisomerase I and topoisomerase II in vitro. Sedanolide displays antimicrobial efficacy against Aedes, Caenorhabditis, Candida, Drosophila, and Panagrellus.
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その他 |
[融点]30℃-31℃ [外観]White solid
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参考文献 |
Tsukamoto T, Ishikawa Y, Miyazawa M. Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem. 2005 Jul 13;53(14):5549-53. PMID: 15998112.Jiao XZ, Xie P, Zu LS, et al. Study of stereoselective synthesis of (+/-)-neocnidilide. J Asian Nat Prod Res. 2003 Sep;5(3):165-9. PMID: 12931848.Momin RA, Nair MG. Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. Phytomedicine. 2002 May;9(4):312-8. PMID: 12120812.Momin RA, Nair MG. Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds. J Agric Food Chem. 2001 Jan;49(1):142-5. PMID: 11305251.
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
-20℃
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