別品名 |
all-trans-Lycopene, Lycopene 7, ψ,ψ-Carotene
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別包装 |
あり
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純度 |
>=90%
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分子量 |
536.88
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CAS RN® |
502-65-8
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化合物の概要 |
Carotene pigment found in red and green fruits and vegetables; RAR agonist.
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構造 |
C40H56
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溶媒 |
Insoluble in water. Sparingly soluble in ethanol. Soluble in carbon disulfide, chloroform and benzene.
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使用目的 |
Lycopene is a carotene found in tomatoes and other red fruits and vegetables; it is occasionally used as a pigment dye. Lycopene exhibits cardioprotective, hepatoprotective, antioxidative, and anticancer activity. Lycopene activates retinoic acid receptors (RARs) but does not exhibit significant vitamin A activity. In cardiomyocytes, lycopene inhibits hypertrophy and Akt/GSK-3β signaling and increases expression of PTEN. In breast cancer cells, this compound induces cell cycle arrest and apoptosis and decreases cellular viability. Additionally, lycopene decreases levels of malondialdehyde and lactate dehydrogenase and increases levels of catalase in animal models of hepatic ischemia/reperfusion.
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その他 |
[融点]172℃-173℃ [外観]Red to Deep Red Powder
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参考文献 |
Chao HH, Sung LC, Chen CH, et al. Lycopene Inhibits Urotensin-II-Induced Cardiomyocyte Hypertrophy in Neonatal Rat Cardiomyocytes. Evid Based Complement Alternat Med. 2014;2014:724670. PMID: 24971153.Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.Bayramoglu G, Bayramoglu A, Altuner Y, et al. The effects of lycopene on hepatic ischemia/reperfusion injury in rats. Cytotechnology. 2014 Mar 4. [Epub ahead of print]. PMID: 24590927.Aydemir G, Carlsen H, Blomhoff R, et al. Lycopene induces retinoic acid receptor transcriptional activation in mice. Mol Nutr Food Res. 2012 May;56(5):702-12. PMID: 22648617.
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メーカー |
品番 |
包装 |
LKT
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L9609
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1 MG
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※表示価格について
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