別品名 Naramycin A, Actidione, Naramycin, NSC-185, A-67, Zygomycin-D, [1S-[1αS*),3α,5β]]-4-[2-(3,5-Dimethyl-2-oxocyclo- hexyl)-2-hydroxyethyl]-2,6-piperidinedione
別包装 あり
純度 >=98%
分子量 281.35
CAS RN® 66-81-9
化合物の概要 Protein synthesis inhibitor, used to measure protein lifespan.
構造 C15H23NO4
溶媒 Soluble in chloroform, DMSO, acetone, methanol, or ethanol. Soluble in water to 20 mg/ml.
使用目的 Cycloheximide was initially produced by Streptomyces. Cycloheximide inhibits protein synthesis in eukaryotes by preventing tRNA translocation and elongation. Cycloheximide is not used in humans due to its high toxicity. In research models, cycloheximide is used to determine protein lifespan and ribosomal profiling.
その他 [融点]119.5℃-121℃
[外観]White to off white powder
参考文献 Bohnert M, Scherer O, Wiechmann K, et al. Melleolides induce rapid cell death in human primary monocytes and cancer cells. Bioorg Med Chem. 2014 Aug 1;22(15):3856-61. PMID: 25028062.Ren Y, D'Ambrosio MA, Garvin JL, et al. Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30. Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F427-34. PMID: 24966088.Greenberger NJ, Ruppert RD. Inhibition of protein synthesis: a mechanism for the production of impaired iron absorption. Science. 1966 Jul 15;153(3733):315-6. PMID: 17780009.


メーカー 品番 包装
LKT C9709 5 G
希望販売価格 ¥46,000


当社在庫 なし
納期目安 1週間程度
保存温度 4℃




メーカー名 LKT Laboratories, Inc.
略号 LKT