別品名 |
Csh cyclosporin, Cyclosporine H
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別包装 |
あり
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純度 |
>=96%
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分子量 |
1202.61
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CAS RN® |
83602-39-5
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化合物の概要 |
Cyclosporin metabolite; formyl peptide inhibitor.
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構造 |
C62H111N11O12
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溶媒 |
Soluble in DMSO, ethanol, acetone, chloroform.
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使用目的 |
Cyclosporin H is a cyclosporin metabolite that inhibits the formyl peptide receptor but not calmodulin. Cyclosporin H lacks immunosuppressive activity but inhibits basophil activation.
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その他 |
[融点]162℃-167℃ [外観]White Crystalline Powder
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参考文献 |
Stenfeldt AL, Karlsson J, Wenneras C, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9. PMID: 17687636.Yan P, Nanamori M, Sun M, et al. The immunosuppressant cyclosporin A antagonizes human formyl peptide receptor through inhibition of cognate ligand binding. J Immunol. 2006 Nov 15;177(10):7050-8. PMID: 17082621.de Paulis A, Ciccarelli A, de Crescenzo G, et al. Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine. J Allergy Clin Immunol. 1996 Jul;98(1):152-64. PMID: 8765829.
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メーカー |
品番 |
包装 |
LKT
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C9614
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5 MG
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
常温
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