別品名 |
Chalkone, trans-Benzylideneacetophenone, 1,3-Diphenyl-2-propen-1-one
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別包装 |
あり
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純度 |
>=97%
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分子量 |
208.26
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CAS RN® |
94-41-7
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化合物の概要 |
Enone.
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構造 |
C15H12O
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溶媒 |
Insoluble in water. Slightly soluble in ethanol.
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使用目的 |
Chalcone is an enone on which a variety of structures are based. Chalcone derivatives typically exhibit anti-inflammatory, antioxidative, neuroprotective, analgesic, anticancer, and anti-parasitic activities.
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その他 |
[融点]54℃-57℃ [外観]Light Yellow Crystal Powder
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参考文献 |
Wu JZ, Cheng CC, Shen LL, et al. Synthetic Chalcones with Potent Antioxidant Ability on H2O2-Induced Apoptosis in PC12 Cells. Int J Mol Sci. 2014 Oct 14;15(10):18525-18539. PMID: 25318055.Jantan I, Bukhari SN, Adekoya OA, et al. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Des Devel Ther. 2014 Sep 16;8:1405-18. PMID: 25258510.Abdellatif KR, Elshemy HA, Salama SA, et al. Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents. J Enzyme Inhib Med Chem. 2014 Sep 8:1-8. PMID: 25198887.Karthikeyan C, Narayana Moorthy NS, Ramasamy S, et al. Advances in Chalcones with Anticancer Activities. Recent Pat Anticancer Drug Discov. 2014 Aug 19. [Epub ahead of print]. PMID: 25138130.Shivahare R, Korthikunta V, Chandasana H, et al. Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents. J Med Chem. 2014 Apr 24;57(8):3342-57. PMID: 24635539.
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メーカー |
品番 |
包装 |
LKT
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C2800
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100 G
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
常温
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