別品名 |
(2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline, Aceplus, Hypertil,Tensoprel, N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline
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別包装 |
あり
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純度 |
>=81%
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分子量 |
217.29
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CAS RN® |
62571-86-2
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化合物の概要 |
ACE inhibitor.
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構造 |
C9H15NO3S
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溶媒 |
Soluble in water or ethanol.
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使用目的 |
Captopril is the first angiotensin-converting enzyme (ACE) inhibitor marketed; it is clinically used to treat hypertension, congestive heart failure (CHF), and diabetic nephropathy. Captopril exhibits antihypertensive, anti-metastatic, and anticancer chemotherapeutic activities. In animal models of lung cancer, captopril decreases tumor growth and metastasis and induces cellular apoptosis.
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その他 |
[融点]104-108℃ [外観]A White to Off-White Crystalline Powder
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参考文献 |
Zidane F, Zeder-Lutz G, Altschuh D, et al. Surface plasmon resonance analysis of the binding mechanism of pharmacological and peptidic inhibitors to human somatic angiotensin I-converting enzyme. Biochemistry. 2013 Dec 3;52(48):8722-31. PMID: 24168709.Attoub S, Gaben AM, Al-Salam S, et al. Captopril as a potential inhibitor of lung tumor growth and metastasis. Ann N Y Acad Sci. 2008 Sep;1138:65-72. PMID: 18837885.
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メーカー |
品番 |
包装 |
LKT
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C0261
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25 G
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
常温
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