別品名 |
Amikacin sulfate, Amikin, Biklin, Lukadin, Mikavir, Novamin, Pierami, O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [6-amino-6-deoxy-α-D-glucopyranosyl-(1->4)]-N1- [(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D- streptamine sulfate
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別包装 |
あり
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純度 |
>=98%
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分子量 |
781.76
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CAS RN® |
39831-55-5
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化合物の概要 |
Aminoglycoside; protein translation inhibitor.
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構造 |
C22H43N5O13 2H2SO4
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溶媒 |
Soluble in water (50mg/mL). Insolulble in acetone and water. DMSO <1 mg/mL.
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使用目的 |
Amikacin is an aminoglycoside antibiotic that exhibits antibacterial efficacy against gram negative bacteria. Amikacin binds the 30S ribosomal subunit, preventing translation.
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その他 |
[融点]220℃-230℃(dec.) [外観]White or Almost White Powder
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参考文献 |
Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. Am J Hosp Pharm. 1977 Jul;34(7):723-37. PMID: 407790.Kawaguchi H. Discovery, chemistry, and activity of amikacin. J Infect Dis. 1976 Nov;134 SUPPL:S242-8. PMID: 825583.King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274.
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
常温
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