別品名 |
L-Sulforaphane, 1-Isothiocyanato-4-(methylsulfinyl)-butane
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純度 |
97%
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分子量 |
177.29
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CAS RN® |
142825-10-3
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化合物の概要 |
ITC found in cruciferous vegetables; AhR antagonist.
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溶媒 |
Soluble in ethanol, methanol, or ethyl acetate. Miscible with water and/or DMSO.
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参考文献 |
Abdull Razis AF, Hanlon N, Soltys E, et al. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Arch Toxicol. 2012 Oct;86(10):1505-14. PMID: 22643862.Zanichelli F, Capasso S, Cipollaro M, et al. Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect. Age (Dordr). 2012 Apr;34(2):281-93. PMID: 21465338.Abdull Razis AF, Bagatta M, De Nicola GR, et al. Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality. Arch Toxicol. 2011 Aug;85(8):919-27. PMID: 21132492.Abdull Razis AF, Iori R, Ioannides C. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82. PMID: 20726001.
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
-20℃
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