| 別品名 |
Resveratrol 3-β-mono-D-glucoside, 3-Hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-beta-D-glucoside
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| 別包装 |
あり
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| 純度 |
>=97%
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| 分子量 |
390.38
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| CAS RN® |
65914-17-2
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| 化合物の概要 |
Stilbenoid glucoside found in Polygonum.
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| 構造 |
C20H22O8
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| 溶媒 |
Soluble in methanol, ethanol acetone, hot water or ethyl acetate.
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| 使用目的 |
Polydatin is a resveratrol-related glucoside originally found in Polygonum cuspidatum. Polydatin exhibits anticancer, anti-inflammatory, antioxidative, and anti-allergic activities. In lung cancer cells, polydatin downregulates expression of cyclin D1 and Bcl-2 and upregulates expression of Bax, inducing cell cycle arrest and apoptosis. In animal models of sepsis, polydatin decreases sepsis-induced mortality and lung injury by suppressing production of COX-2, iNOS, and inflammatory cytokines. Polydatin also decreases the loss of mucosal barrier integrity in the small intestine due to OVA-induced allergy by inhibiting mast cell degranulation.
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| その他 |
[融点]223-226 oC
[沸点]707.7℃
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| 参考文献 |
Zhang Y, Zhuang Z, Meng Q, et al. Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest. Oncol Lett. 2014 Jan;7(1):295-301. PMID: 24348867.Yang B, Li JJ, Cao JJ, et al. Polydatin attenuated food allergy via store-operated calcium channels in mast cell. World J Gastroenterol. 2013 Jul 7;19(25):3980-9. PMID: 23840142.Li XH, Gong X, Zhang L, et al. Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1. Mediators Inflamm. 2013;2013:354087. PMID: 23431240.Wu MJ, Gong X, Jiang R, et al. Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice. Int J Immunopathol Pharmacol. 2012 Oct-Dec;25(4):923-34. PMID: 23298483.
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※表示価格について
| 当社在庫 |
なし
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| 納期目安 |
1週間程度
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| 保存温度 |
常温
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