別品名 |
PD-1 Antibody: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PD1, Programmed cell death protein 1, Protein PD-1, PDCD1, PDCD-1
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抗原部位 |
Extracellular domain
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種由来 |
Human
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標識物 |
Unlabeled
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精製度 |
Ig fraction - Protein A
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適用 |
Western Blot IHC paraffin embedding section Enzyme Linked Immunosorbent Assay Immuno Fluorescence Immunocytochemistry (cell) Flow Cytometry
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免疫動物 |
Mouse
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抗体クラス |
IgG1
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クローン |
4C7
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交差種 |
Human
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GENE ID |
5133
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Accession No.(Gene/Protein) |
NP_005009
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Gene Symbol |
PDCD1
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形状 |
液状
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推奨品 |
ポジティブコントロール 品番:1306 - Human Spleen Tissue Lysate, ポジティブコントロール 品番:1315 - Human Tonsil Tissue Lysate, ポジティブコントロール 品番:1369 - Human Lymph Node Tissue Lysate, ポジティブコントロール 品番:1208 - THP-1 Cell Lysate
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その他 |
[Protein GI Number]145559515 [Swiss-Prot No]Q15116
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参考文献 |
Holling TM, Schooten E, and van Den Elsing PJ. Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. Hum. Immunol. 2004; 65:282-90. Ishida Y, Agata Y, Shibahara K, et al. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992; 11:3887-95. Zhong X, Bai C, Gao W, et al. Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. Int. Immunol. 2004; 16:1181-8. Nishimura H, Nose M, Hiai H, et al. Development of lupus-like autoimmune diseases by the disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999; 11:141-51.
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Immunocytochemistry of PD-1 in transfected 293 cells with PD-1 [4C7] antibody at 10 μg/mL. Lower left: Immunocytochemistry in transfected 293 cells with control mouse IgG antibody at 10 μg/mL.
(A) Immunohistochemistry of PD-1 in human breast cancer tissue with PD-1 [4C7] antibody at 10 μg/mL. (B) Immunohistochemistry in human breast cancer tissue with control mouse IgG staining at 10 μg/mL.
Immunofluorescence of PD-1 in human breast cancer tissue with PD-1 [4C7] antibody at 10 μg/mL.
Green: PD1 Antibody [4C7] (RF16004) Blue: DAPI staining
Flow cytometry analysis of PD-1 transfected 293 cells using PD-1 [4C7] antibody at 1 μg/ml. Blue: untransfected cells, Yellow: PD-1 transfected cells.
Titration curve analysis of PD-1 mAbs to detect recombinant PD-1 in ELISA with RF16001, RF16002, RF16003, RF16004, and RF16005 abs at decreasing concentrations.
A sandwich ELISA was performed using the anti-PD-1 mAbs RF16001, RF16002, RF16003, RF16004, and RF16005 as the capture antibodies for the PD-1 extracellular domain antigen with HRP-labeled Risk-Free anti-PD-1 mAbs as the detection antibodies.
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Immunocytochemistry of PD-1 in transfected 293 cells with PD-1 [4C7] antibody at 10 μg/mL. Lower left: Immunocytochemistry in transfected 293 cells with control mouse IgG antibody at 10 μg/mL.
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メーカー |
品番 |
包装 |
PSC
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RF16004
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0.1 MG [1 mg/mL]
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※表示価格について
当社在庫 |
なし
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納期目安 |
3週間程度
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保存温度 |
-20℃
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