| 別品名 |
Nerve Growth Factor 7S
|
| 種由来 |
Mouse
|
| 発現系 |
Native
|
| 純度 |
98%
|
| 分子量 |
130kDa
|
| CAS RN® |
93928-24-6
|
| 化合物の概要 |
Native Mouse Nerve Growth Factor 7S
|
| その他 |
[内容･その他(内容)]This 7S nerve growth factor protein is a precursor of 2.5S NGF and is purified from the male mouse submaxillary glands by a modification of the procedure described by Darling and Shooter (1984)(1).
|
| 参考文献 |
1. Darling, T. and Shooter, E. M. (1984) "Methods for preparation and assay of nerve growth factor", Cell Culture Methods for Molecular and Cellular Biology, vol. 4 (Eds. D.W. Barnes, D.A. Sinbasku, and G.H. Sato), pp. 79-83, Alan R. Liss, NewYork. Varon, S., et al (1967) Biochem. 6, 2202. Lowry, O. H., et al. (1951) J. Biol.Chem. 193, 265.
神経成長因子(NGF:nerve growth factor)は､神経軸策の伸長及び神経伝達物質の合成促進作用､､神経細胞の維持作用､細胞損傷時の修復作用､脳神経の機能・復を促し老化を防止する作用等を持ち合わせた重要なﾀﾝﾊﾟｸ質です｡特に､樹状突起の機能低下を防ぐ働きがｱﾙﾂﾊｲﾏｰ病や痴呆症の予防･治療に有効であると注目されています｡
|
|
※サムネイル画像をクリックすると拡大画像が表示されます。
Alomone Labs Native mouse NGF 7S protein promotes neurite outgrowth and survival？in PC12 cells. - Upper panel: Cells were grown on collagen-coated plates in the absence or presence of 5 ng/ml Native？mouse NGF 7S protein？(#N-130). The development of neurites over a period of 3 days was visualized by Methylene Blue staining. Lower panel: Cells were grown in the absence of serum and in the presence of varying concentrations of Native mouse NGF 7S protein or？Native mouse NGF 2.5S protein (>95%)？(#N-100). Cell survival after 24 h was measured by the XTT method and calculated as a relative percentage of the control and plotted against concentrations used.
|
|
|
|
Alomone Labs Native mouse NGF 7S protein promotes neurite outgrowth and survival？in PC12 cells. - Upper panel: Cells were grown on collagen-coated plates in the absence or presence of 5 ng/ml Native？mouse NGF 7S protein？(#N-130). The development of neurites over a period of 3 days was visualized by Methylene Blue staining. Lower panel: Cells were grown in the absence of serum and in the presence of varying concentrations of Native mouse NGF 7S protein or？Native mouse NGF 2.5S protein (>95%)？(#N-100). Cell survival after 24 h was measured by the XTT method and calculated as a relative percentage of the control and plotted against concentrations used.
|
|
|
| メーカー |
品番 |
包装 |
|
ALO
|
N-130
|
0.5 MG
|
※表示価格について
| 当社在庫 |
なし
|
| 納期目安 |
約10日
|
| 保存温度 |
-２０℃
|
|
