種由来 |
Mouse
|
適用 |
Functional Assay
|
免疫動物 |
Mouse
|
クローン |
MAR1-5A3
|
添加剤 |
Low Endotoxin, Azide Free, Carrier Free
|
使用目的 |
Functional Assay: Clone MAR1-5A3 has a short half-life, basically because every cell expresses the IFNAR1 receptor and the receptor recycles very rapidly. And, if you want to block function in vivo, you need to be sure that all of the receptors are blocked continually in all compartments. Therefore, you need a large in vivo loading dose (2.5 mg/mouse) to saturate all the binding sites in vivo and then maintain a high enough level to keep them saturated. For in vivo blocking studies we recommend give a loading dose of 2.5 mg/mouse and follow with a weekly dose of 0.5 mg/mouse. The half-live following a 2.5 mg loading dose is about 5 days. [However, if you only inject a low dose of 250 micrograms, then the half life is 1.5 days ? because you haven’t saturated the mouse].
|
|
メーカー |
品番 |
包装 |
LET
|
I-1188
|
100 MG
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
2週間程度
|
保存温度 |
4℃
|
|