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The recombinant human synuclein family (alpha-,beta- and gamma-) (each 20ng), Mouse brain and Rat brain (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human alpha,beta-synuclein (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
ICC/IF analysis of alpha, beta-Synuclein in LNCaP cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human alpha, beta-Synuclein antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
ICC/IF analysis of alpha, beta-Synuclein in U87MG cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human alpha, beta-Synuclein antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
ICC/IF analysis of alpha, beta-Synuclein in C6 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human alpha, beta-Synuclein antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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The recombinant human synuclein family (alpha-,beta- and gamma-) (each 20ng), Mouse brain and Rat brain (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human alpha,beta-synuclein (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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| 別品名 |
a, b - synuclein, Alpha synuclein, Beta synuclein, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, PARK1, PARK4, Parkinson disease familial 1, PD1, SNCA, SNCB, SNCB protein, Synuclein alpha, Synuclein beta,
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| 種由来 |
Human
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| 交差種 |
Human
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| 適用 |
Western Blot
Enzyme Linked Immunosorbent Assay
Immuno Fluorescence
Immunocytochemistry (cell)
Flow Cytometry
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| 免疫動物 |
Mouse
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| クローン |
3B6
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| 抗体クラス |
IgG1κ
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| 抗原部位 |
a.a.119-140
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| 標識物 |
Unlabeled
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| 精製度 |
Ig fraction - Protein G
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| Accession No.(Gene/Protein) |
NP_000336, NP_003076, P37840, Q16143
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| 概要 |
alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.
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| 参考文献 |
Jakes R., et al. (1994) FEBS lett. 345, 27-32
Ueda K., et al. (1993) Proc. Natl.Acad. Sci. USA 90, 11282-11286
Kim J. (1997) Molecules and Cells 7, 78-83
Paik S. R., et al. (1997) Arch. Biochem. Biophys. 344, 325-334.
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| メーカー |
品番 |
包装 |
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ATG
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ASC0632
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100 UL
[1mg/ml]
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※表示価格について
| 当社在庫 |
なし
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| 納期目安 |
1週間程度
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| 保存温度 |
-７０℃
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