CAS RN® |
1033769-28-6
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化合物の概要 |
A Potent pan-Trk (Neurotrophin Receptor) Inhibitor
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ManufacturerBioassayAlomone Labs GNF 5837 inhibits BDNF induced ERK1/2 MAPK phosphorylation in TrkB stably expressed in HEK 293 cells. - Cells were serum deprived for 2 hrs followed by a 10 min stimulation with 10 ng/ml?Recombinant human BDNF protein?(#B-250) (lane 2), 10 and 100 μM?GNF 5837?(#G-145) preincubated with 10 ng/ml Recombinant human BDNF protein for 10 min (lanes 3 and 4, respectively). Control cells incubated without Recombinant human BDNF protein are shown in lane 1. Cell proteins were resolved by SDS-PAGE and detected with anti-phospho-ERK1/2.
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ManufacturerBioassayAlomone Labs GNF 5837 inhibits BDNF induced ERK1/2 MAPK phosphorylation in TrkB stably expressed in HEK 293 cells. - Cells were serum deprived for 2 hrs followed by a 10 min stimulation with 10 ng/ml?Recombinant human BDNF protein?(#B-250) (lane 2), 10 and 100 μM?GNF 5837?(#G-145) preincubated with 10 ng/ml Recombinant human BDNF protein for 10 min (lanes 3 and 4, respectively). Control cells incubated without Recombinant human BDNF protein are shown in lane 1. Cell proteins were resolved by SDS-PAGE and detected with anti-phospho-ERK1/2.
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メーカー |
品番 |
包装 |
ALO
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G-145
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100 MG
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※表示価格について
当社在庫 |
なし
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納期目安 |
約10日
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保存温度 |
-20℃
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