別品名 |
(-)-Rapamycin; AY 22989; Antibiotic AY 22989; Cypher; NSC 226080; RAPA; RPM; Rapammune; Rapamune; SIIA 9268A; Sirolimus; Wy 090217;
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分子量 |
914.17
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CAS RN® |
53123-88-9
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構造 |
C51H79NO13
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溶媒 |
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
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使用目的 |
A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa'Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It has shown its efficacy against neurodegenerative diseases including Alzheimer's and Parkinson's.
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その他 |
[融点]170-173℃ [性状]White to Pale Yellow Solid
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参考文献 |
Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),
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メーカー |
品番 |
包装 |
TRC
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R124000
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100 MG
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※表示価格について
当社在庫 |
なし
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納期目安 |
2週間程度
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保存温度 |
-20℃
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