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※サムネイル画像をクリックすると拡大画像が表示されます。
Fig. 1: The extract of Jurkat (40ug), A549(40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Fig. 2: The Human Recombinant protein PDCL3(100ng) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
ICC/IF analysis of PDCL3 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PDCL3 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
ICC/IF analysis of PDCL3 in PC3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PDCL3 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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Fig. 1: The extract of Jurkat (40ug), A549(40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Fig. 2: The Human Recombinant protein PDCL3(100ng) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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| 別品名 |
Phosducin-Like protein 3, Phosducin-Like protein 3, HTPHLP, MGC3062, PHLP2A, PHLP3, VIAF, VIAF1
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| 種由来 |
Human
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| 交差種 |
Human
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| 適用 |
Western Blot
Enzyme Linked Immunosorbent Assay
Immuno Fluorescence
Immunocytochemistry (cell)
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| 免疫動物 |
Mouse
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| クローン |
AT8F9
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| 抗体クラス |
IgG1κ
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| 抗原部位 |
a.a.1-239
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| 標識物 |
Unlabeled
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| 精製度 |
Ig fraction - Protein A
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| Accession No.(Gene/Protein) |
NP_076970, Q9H2J4
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| 概要 |
PDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as beta Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates.
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| 参考文献 |
Wilkinson J.C., et al. (2004) Biol. Chem. 279(49):51091-51099
Hillier L.W., et al. (2005) Nature 434(7034):724-731
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| メーカー |
品番 |
包装 |
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ATG
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ATGA0333
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50 UL
[1mg/ml]
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※表示価格について
| 当社在庫 |
なし
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| 納期目安 |
1週間程度
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| 保存温度 |
-７０℃
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