@charset "UTF-8";

/*
html5doctor.com Reset Stylesheet
v1.6.1
Last Updated: 2010-09-17
Author: Richard Clark - http://richclarkdesign.com
Twitter: @rich_clark
*/

html, body, div, span, object, iframe,
h1, h2, h3, h4, h5, h6, p, blockquote, pre,
abbr, address, cite, code,
del, dfn, em, img, ins, kbd, q, samp,
small, strong, s/ub, s/up, var,
b, i,
dl, dt, dd, ol, ul, li,
fieldset, form, label, legend,
table, caption, tbody, tfoot, thead, tr, th, td,
article, aside, canvas, details, figcaption, figure,
footer, header, hgroup, menu, nav, section, summary,
time, mark, audio, video {
    margin:0;
    padding:0;
    border:0;
    outline:0;
    font-size:100%;
    vertical-align:baseline;
    background:transparent;
}

body {
    line-height:1;
}

article,aside,details,figcaption,figure,
footer,header,hgroup,menu,nav,section {
    display:block;
}

nav ul {
    list-style:none;
}

blockquote, q {
    quotes:none;
}

blockquote:before, blockquote:after,
q:before, q:after {
    content:'';
    content:none;
}

a {
    margin:0;
    padding:0;
    font-size:100%;
    vertical-align:baseline;
    background:transparent;
}

/* change colours to suit your needs */
ins {
    background-color:#ff9;
    color:#3f3f3f;
    text-decoration:none;
}

/* change colours to suit your needs */
mark {
    background-color:#ff9;
    color:#3f3f3f;
    font-style:italic;
    font-weight:bold;
}

del {
    text-decoration: line-through;
}

abbr[title], dfn[title] {
    border-bottom:1px dotted;
    cursor:help;
}

table {
    border-collapse:collapse;
    border-spacing:0;
}

/* change border colour to suit your needs */
hr {
    display:block;
    height:1px;
    border:0;  
    border-top:1px solid #cccccc;
    margin:1em 0;
    padding:0;
}

input, select {
    vertical-align:middle;
}





/* *************************************** */
/* PC style */
html {
  font-size: 62.5%;/*pxだと10px;*/
  font-family:"メイリオ",Meiryo,"ヒラギノ角ゴ Pro W3","Hiragino Kaku Gothic Pro","ＭＳ Ｐゴシック","MS P Gothic",sans-serif;
  color: #333;
}

:root {
  --main-color: #4472C4;
  --basic-width: 936px;
}

body {
  margin: 0;
  padding: 0;
}
header,
main,
footer {
  /*width: var(--basic-width);*/
  margin: 0 auto;
}
.fv01{
  /*max-width: 1400px;*/
  margin: 0 auto;
 /* padding: 0 40px; */
  background: #fff;
}
.intro01{
 /* max-width: 1350px;*/
  margin: 0 auto;
  margin-bottom: 8em;
  background: url(../images/puromycin_bg01.png) no-repeat center;
  background-size: cover;
  position: relative;
    padding-bottom:4em ;
}
.puromycin-section01{

/*  background:#F2F2F2 ;*/
background: #fff;
margin-bottom: 8em;
}
.puromycin-section02{

/*  background:#F2F2F2;*/
margin-bottom: 8em;
background: #fff;
}
.puromycin-section03{

  /*  background:#F2F2F2 ;*/
  background: #b40808;
  margin-bottom: 8em;
  }

.puromycin-section04{
  background: #b40808;
  padding-bottom: 8em;
}

.puromycin-section05{
  background: #fff;
}

.scientist-section01{
  padding-bottom: 8em;
 /* background-image: url(../images/background_img01.png);
  background-repeat: no-repeat;
  background-position: center;
  background-size: cover;
  background-color:rgba(255,255,255,0.4);
  background-blend-mode:overlay;*/

}

.scientist-section01-inner01{
  max-width: 1920px;
  margin: 0 auto;
}
.maker01{
  max-width: 1200px;
  margin: 0 auto;
}
.target_base01{
  background-color: #EDEDED;
    padding: 40px 0;
}
.phenotype01{
  background-color: #E2F0D9;
  padding: 40px 0;
}
.modality01{
  background-color: #DEEBF7;
  padding: 40px 0;
}

a {
  font-weight: bold;
  text-decoration: none;
}
a:hover {
 /* text-decoration: underline;*/
}

p,li {
  font-size: 1.9rem;
  line-height: 1.75;
  margin: 0;
}

img {
  max-width: 100%;
  height: auto;
}

a img:hover {
  opacity: 0.8;
}

header img {
  width: 100%;

}



/* ------------------- */


h1 {
  color: #3f3f3f;
  font-size: 7.8rem;
  font-weight: bold;
  margin: 0 0 20px 0;
  padding: 0 0 5px 0;
}


section h2 {
  color: #3f3f3f;
  font-size: 2.8rem;
  font-weight: bold;
  margin: 1.2rem 0 0 0;
  padding: 0 0 5px 0;
  text-align: left;
  /border: yellow solid 1px;

}
.button-center01{
  text-align: center;
}
.button01{
  display: block;
  padding: 30px 90px;
  font-size: 24px;
  line-height: 1.43;
  background: #4472C4;
  color: #3f3f3f;
  margin: 0 200px 40px ;

}

h3 {
  color: #3f3f3f;
  font-size: 2.7rem;
  line-height: 1.75;
  font-weight: bold;

}


/* ------------------- */




.text_intro {
  text-align: center;
  text-decoration: underline;
  font-size: 2rem;
}
.text_title01 {
  text-align: left;
  font-size: clamp(2.1rem, 1.8vw, 2.7rem);
  color: #3f3f3f;
  margin: 10px 0;
}
.text_left01 {
  text-align: left;
  width: 98%;
 /* font-size :1.55rem;*/
 font-size: clamp(1.2rem, 1.5vw, 1.8rem);
 display: table-cell;
}
.text_left03 {
  text-align: left;
  width: 82%;
  font-size: clamp(1.0rem, 1.29vw, 1.8rem);
}

.text_left01:nth-child(5) {
  text-align: left;
  width: 85%;
}
.text_left02 {
  text-align: left;
  font-size: 1.9rem;
}


.catch01 {
  color: var(--main-color);
  font-size: 2rem;
  font-weight: bold;
}
.catch02 {
  color: #3f3f3f;
  font-size:2.0rem;
  font-weight: normal;
  margin: 0;
  line-height: normal;
  max-width: 1200px;
  display: block;
  margin: 0 auto;
}
.catch03 {
  color: #3f3f3f;
  font-size:2.0rem;
  font-weight: bold;
  margin: 2em 0;
  text-align: center;

}
.catch04 {
  color: #3f3f3f;
  font-size:2.0rem;
  font-weight: normal;
  margin: 0;
  line-height: normal;
  
}
.puromycin-text01{
  max-width: 970px;
  margin-bottom: 50px!important;
}
.puromycin-text02{
  max-width: 1100px;
  margin-bottom: 40px!important;
  margin-top: 40px!important;
  /*font-weight: bold;*/
  -webkit-text-stroke: 0.5px #3f3f3f;

}
.puromycin-text03{
  font-size: 1.4em;
  color: #3f3f3f;


}
.puromycin-text04{
  max-width: 1100px;
  margin: 0 auto;
  color: #3f3f3f;
    font-size: 1.75rem;
    line-height: 2.4rem;
    -webkit-text-stroke: 0.5px #3f3f3f;

}
.puromycin-text05{
  font-size: 1.6em;
  color: #fff;
}
.puromycin-text06{
  font-size: 1.75em;
  color: #fff;
  margin-top: 5px;
}
.puromycin-text07 {
}
.puromycin-text07 p {
  margin-bottom: 1.5rem !important;
}
.puromycin-text08{
  max-width: 970px;
  margin-bottom: 2rem !important;
}
.puromycin-text08-01{
  max-width: 970px;
  margin-top: 2rem !important;
  margin-bottom: 1.5rem !important;
}

.puromycin-fv-text01{
  color: #fff!important;
  font-size: 2.8rem!important;
  line-height: 3.4rem!important;
  margin-bottom: 40px;
  font-weight: bold;
  line-height: normal;

}

.puromycin-fv-text02{
  color: #f1ae00!important;
  font-size: 7.5rem!important;
  text-align: center;
  margin-bottom: 40px;
  text-shadow: #919191 2px 4px 5px;
}
.puromycin-fv-inner-text02{
  font-size: 2.8rem!important;
  color: #ffffff;
}

.items-border {
 /* border: solid 1px #3f3f3f;*/
 max-width: 1350px;
  border-radius: 30px;
  padding: 0 1em;
  margin: 0 auto;


}
.items-border02 {
  padding: 0 40px;
}

.makerimg01 {
  border-radius: 30px;
  max-width: 1180px;
  text-align: center;
  padding: 0;
  background: #fff;
  width: 100%;
  margin: 0 auto;

}

.makerimg01 p{
  text-align: left;
  color: #3f3f3f;
  font-size: 1.75rem;
  line-height: 2.4rem;
  margin: 0;
  -webkit-text-stroke: 0.5px #3f3f3f;
}

.makerimg02 {

  font-size: 0;
  text-align: center;
  padding: 0;

  width: 100%;
  display:flex; 
  justify-content:space-evenly;
  /*flex-flow:row wrap;*/
  max-width: 1180px;
  margin: 0 auto;
  
 

}

.makerimg02 div {
  width: calc( 50% - 5px );
  margin-right: 12px;

 /* text-align: -webkit-center;*/

  padding: 0 10px;
}
.makerimg02 p{
  text-align: left;
  color: #3f3f3f;
  font-size: 1.75rem;
  line-height: 2.4rem;
  margin: 0;
  margin-top: 60px;
  /*font-weight: bold;*/
  -webkit-text-stroke: 0.5px #3f3f3f;
}

.makerimg02 a {
  display: inline-block;
 /* margin: 0 20px;*/
}
.makerimg02 .icon_img {
  display: inline-block;
  margin: 0 20px 20px;
  max-width: auto;
}

.fv-makerimg02 {
  font-size: 0;
  text-align: center;
  padding: 0;
  width: 100%;
  display:flex; 
  justify-content:space-evenly;
  /*flex-flow:row wrap;*/
}

.fv-makerimg02 .puromycin-main-title01{
  width: calc( 50% - 5px );
  margin-right: 12px;

 /* text-align: -webkit-center;*/

  padding: 0 10px;
}
.fv-makerimg02 .puromycin-background01{
  width: calc( 50% - 5px );
  margin-right: 12px;
  margin-right: 0;

 /* text-align: -webkit-center;*/

  padding: 0 10px;
}
.puromycin-background01 img {
  width: 40%;
  filter: drop-shadow(5px 5px 5px #6e6e6e);
}

.makerimg03 {
 margin-bottom: 60px;
  width: 100%;
  display:flex; 
  margin-top: 60px;
  /border: greenyellow solid;
}

.makerimg03 div {
  width: calc( 50% - 5px );
  margin-right: 12px;


  padding: 0 10px;
}

.makerimg03 a {
  display: inline-block;
  margin: 0 20px;
}

.makerimg03 .icon_img {
  display: inline-block;
  margin: 0 20px;
}

.fv-makerimg03 {
  margin-bottom: 20px;
   width: 100%;
   display:flex; 
   justify-content: space-evenly;
   /* flex-flow: row wrap; */
   max-width: 1100px;
   margin: 0 auto;
 }
.makerimg04 {
  margin-bottom: 20px;
   width: 100%!important;
   display:flex; 
   justify-content:space-evenly;
   /*flex-flow:row wrap;*/
 }

 
/* ------------------- */
/* 汎用 */
.fr {
  float: right;
  margin-left: 25px;
}

.fl {
  float: left;
  margin-right: 20px;
}

.fc {
  clear: both;
}

.cen {
  text-align: center;
}

.break {
  display: none;
}

.mb0 {
  margin-bottom: 0;
}
.mb10 {
  margin-bottom: 10px;
}
.mb20 {
  margin-bottom: 20px;
}
.mb30 {
  margin-bottom: 30px;
}
.mb40 {
  margin-bottom: 40px;
}
.mb50 {
  margin-bottom: 50px;
}
.pt10 {
  padding-top: 10px;
}



/* ------------------- */
/* フッター */
footer #copy {
  margin: 0;
  padding: 1em 0 1em 0;

  font-size: 1.1em;
  text-align: center;
  background-color: #fff;
  color: #3f3f3f;
  font-weight: bold;
  font-family: "メイリオ";
}



/* ------------------- */
/* ページTOPに戻る */
#page_top{
  width: 55px;
  height: 55px;
  position: fixed;
  right: 0;
  bottom: -55px;
  background: #b40808;
  border-radius: 50%;
  border: solid 3px #fff;
}
#page_top a{
  position: relative;
  display: block;
  width: 55px;
  height: 55px;
  text-decoration: none;
}
#page_top a::before{
  font-weight: 900;
  content: '^';
  font-size: 25px;
  color: #FFF;
  position: absolute;
  /width: 25px;
  height: 25px;
  height: 36px;
  /top: -5px;
  bottom: 0;
  right: 0;
  left: 0;
  margin: auto;
  text-align: center;
}
.puromycin-main-title01{
  color: #3f3f3f;
  margin-bottom: 40px;
  margin-top: 40px;
  font-size: 3.6rem;
  font-weight: bold;
}
.puromycin-title01{


  color: #3f3f3f;
  font-size: 4.0rem;
  font-weight: bold;
  padding: 0px;
  padding-right:40px;
  background: linear-gradient(transparent 65%, #f7d783 0%);
  display: inline-flex;
  text-shadow: #b3b3b3 2px 3px 2px;
  white-space: nowrap;
}


.puromycin-title02{

  color: #3f3f3f;
  font-size: 4.2rem;

  font-weight: bold;
  padding: 0px;
  background: linear-gradient(transparent 65%, #f7d783 0%);
  display: inline-flex;
  text-shadow: #b3b3b3 2px 3px 2px;
  padding-right: 40px;
}



.puromycin-title03{

  color: #3f3f3f;
  font-size: 4.2rem;

  font-weight: bold;
  padding: 0px;
  background: linear-gradient(transparent 65%, #f7d783 0%);
  display: inline-flex;
  text-shadow: #b3b3b3 2px 3px 2px;
  padding-right: 40px;
}


a.button01.for-contact {
  margin-top:20px;
  background: #F3AF81;
}

.fv01-img01{
  border: #ccc solid 1px;
}
header{
  display: flex;
  justify-content: space-between;
  max-width: 1350px;
}
footer{


}
.footer-flex{
  display: flex;
  justify-content: space-between;

  margin: 20px auto;
    max-width: 1350px;
}

.logo01{
  padding: 20px 20px;
  margin: 10px 0;
  display: block;
}
.logo01 img{
  height: 50px;
}
.logo02{
  padding: 30px 20px;
}
.logo02 img{
  height: 40px;
}
.logo03{
  padding: 20px 20px;
  margin: 10px 0;
  display: block;
}
.logo03 img{
  height: 50px;
}
.heading_title01{
  color: #fff;
  margin: 0 0 40px 0;
  margin: 25px 0 40px 0;
  text-shadow: #6e6e6e 2px 4px 5px;
  
}
main{
  background: #b40808;
    padding-bottom: 8em;
}







.makerimg02 .puromycin-flex01{
  display: flex;
  justify-content: space-evenly;
  margin-bottom: 10px;
  margin-top: -5px;
  background: none;
  padding-left: 0;
}
.puromycin-flex01{
  width: 100%!important;
}
.puromycin-flex-text01{
  display: flex;
  align-items: flex-end;
  width: calc(50% - 5px);
  font-weight: bold;
}
.puromycin-flex-text02{
  display: flex;
  align-items: flex-end;
  width: calc(50% - 5px);
  font-weight: bold;
  justify-content: center;
}

.puromycin-text01 img{
  width: 100%;

}
.puromycin-pic01{
  width: 100%!important;
  text-align: center;
  /border: pink solid;
}
.puromycin-pic01 img{
  width: 100%;
  /border: greenyellow solid;
}

.puromycin-flex-inner01{
  width: calc( 70% - 5px )!important;
  width: calc( 80% - 5px )!important;
  width: 80% !important;
  text-align: left;
  padding-top: 3rem !important;
  background: #fff;
  /border: blue solid 1px;
}

.puromycin-flex-inner01 ul {
  padding-left: 25px;
}
.puromycin-flex-inner01 ul li {
  font-size: 1.65rem;
}

.puromycin-flex-inner02{
  width: calc( 30% - 5px );
  width: 42% !important;
  /border: yellow solid 1px;
}

.puromycin-flex-inner02-01{
  margin-right: 30px!important;
  width: calc(50% - 5px)!important;
}
.puromycin-flex-inner03{
  width: auto;
  border-radius: 50px;
  padding: 1.5rem 6rem;
  padding-bottom: 60px;
  text-align: left;
  padding-top: 3rem;
}

.puromycin-flex-inner04{
  width: calc( 50% - 5px )!important;
}

.puromycin-flex-inner03 table{
  width: 100%;
  margin: 0 0 5px 0;

}
.puromycin-flex-inner03 th{
  font-size: 1.6rem;
  text-align: center;
  background: #efefef;
  padding: 1em;
  border: 1px solid #ccc;
}
.puromycin-flex-inner03 td{
  font-size: 1.6rem;
  text-align: left;
  background: #ffffff;
  padding: 1em;
  border: 1px solid #ccc;
  -webkit-text-stroke: 0.5px #3f3f3f;
}


.puromycin-flex-inner05{
  width: calc( 70% - 5px )!important;
}

.puromycin-flex-inner06{
  width: calc( 32% - 5px )!important;
}
.puromycin-flex-inner07{
  width: calc( 50% - 5px )!important;
}

.puromycin-flex-inner08{
  width: calc( 50% - 5px )!important;
}

.puromycin-flex-button01{
display: flex;
justify-content: space-around;
}


.puromycin-logo-inner01{

}
.puromycin-logo-inner01 img{
  width:48% ;
  filter: drop-shadow(5px 5px 5px #6e6e6e);
  padding-left: 80px;
}

.puromycin-background01{
  text-align: center;
  margin-top: 40px;
}


.puromycin-button01{

  /* height: 100px; */
  background: url(../images/03_01_puromycin_button01.png) no-repeat center center;
  background-size: contain;
  font-size: 2.8rem;
  line-height: 2.4rem;
  font-weight: bold;
  text-align: center;
  display: block !important;
  /* padding-top: 25px; */
  margin: 0 auto;
  padding: 20px;
  text-decoration: none;

}

.puromycin-inner-button01{
  margin: 0 auto;
  width: 45% !important;
  display: block;
  margin-bottom: 30px;
}

.puromycin-text-button01{
  text-decoration: none;
  color: #FFFFFF;
  font-size: 2.3rem;
  line-height: 1.5em;
}

a.puromycin-button01:hover {
  transform: translateY(-10px);
  /* box-shadow: 0 5px 10px black; */
  /* transform: translate(0, -5px); */
  transition: 0.2s;
}

.puromycin-button02{

  /* height: 100px; */
  background: url(../images/06_02_puromycin_button01.png) no-repeat center center;
  background-size: contain;
  font-size: 2.8rem;
  font-weight: bold;
  text-align: center;
  display: block !important;
  /* padding-top: 25px; */
  margin: 0 auto;
  padding: 20px;
  text-decoration: none;


}
a.puromycin-button02:hover {

  transform: translateY(-10px);
  /* box-shadow: 0 5px 10px black; */
  /* transform: translate(0, -5px); */
  transition: 0.2s;
}
.puromycin-inner-button02{
  margin: 0 auto;
  width: 100% !important;
  display: block;
  margin-bottom: 60px;
}
.puromycin-text-button02{
  text-decoration: none;
  color: #FFFFFF;
  font-size: 2.3rem;
  line-height: 1.5em;
}


.puromycin-bold-text01{
  font-weight: bold;
}
/.puromycin-bold-text01-01{
/margin-bottom: 1rem!important;
}

.puromycin-pic01-hide-pc{
  display: none;
}

.text-center01{
  text-align: center!important;
}

@media screen and (max-width: 1350px) {
.fv-makerimg02 .puromycin-background01{
  text-align: right;
  }
.puromycin-logo-inner01 img{
  width:55% ;
  filter: drop-shadow(5px 5px 5px #6e6e6e);
  padding-right: 30px;
}
}

@media screen and (max-width: 1050px) {
  .puromycin-flex-inner01{
    width: calc( 55% - 5px )!important;
    text-align: left;
    padding-top: 2rem!important;
    background: #fff;
  }

  .puromycin-logo-inner01 img{
    width:55% ;
    filter: drop-shadow(5px 5px 5px #6e6e6e);
    padding-right: 20px;
  }
  .puromycin-flex-inner02-01{
    margin-right: 30px!important;
    width: calc(50% - 5px)!important;
  }
  .puromycin-title01{
    white-space: normal;

  }
  
  }
  


@media screen and (max-width: 900px) {

  .puromycin-flex-inner07{    
    width: calc(60% - 5px) !important;
}
.puromycin-flex-inner08{
  width: calc(40% - 5px) !important;
}

}


/* SP style */
@media screen and (max-width: 768px) {
  body {
    padding: 0 ;
  }

header,
main,
footer {
  width: 100%;
  margin: 0 auto;
}
h1 {
  color: #3f3f3f;
  font-size: 6rem;
  line-height: 3rem;
  font-weight: bold;
  margin: 0 0 20px 0;
  padding: 0 0 5px 0;
}
article h1 {
  text-align: center;
  margin: 20px 0;
}
section h2 {
  font-size: 1.8rem;
  margin: 0px 0 40px 0;
  line-height: 2.4rem;
}


h3 {
  font-size: 1.7rem;
}
h3 span {
  display: block;
}
p, li{
  font-size: 1.62rem;
}

.button01{
  display: block;
  padding: 18px 80px;
  font-size: 1.6rem;
  line-height: 1.43;
  background: #4472C4;
  color: #3f3f3f;
 /* border-radius: 50px;*/
  margin: 0 20px 40px ;

}
 

.catch02 {
  color: #3f3f3f;
  font-size: 1.62rem;
  font-weight: normal;
}
.text_intro {
  font-size: 1.6rem;
}
.mensen {
  margin: 0;
}
.items-border {
  /*border: solid 1px #3f3f3f;*/
  border-radius: 30px;
  padding: 10px 20px;
  margin: 0 ;

}
.items-border02 {
  padding: 10px;
  margin: 0 ;

}

.makerimg01 {
  width: 100%;
}

  
.makerimg02 {
  width: 100%;
  display: block;
}


.makerimg02 div{
  width: calc( 100% - 0px );
  /*margin-bottom: 60px;*/
  padding: 0;
  margin-right: 0;

}
.makerimg02 img {
   width:100%;
}

.makerimg03 {
  width: 100%;
  margin-bottom: 0;
}

.makerimg03 div {
  width: calc( 50% - 0px );
  margin-right: 0px;
  margin-bottom: 12px;
}

.makerimg03 img {
   width:100%;
}

.break {
  display: none;
}
.target_base01{
  padding:  0;
}
.phenotype01{
  padding:  0;
}
.modality01{
  padding:  0;
}
.intro01{
  margin-bottom: 8em;
}
.puromycin-title01{
  font-size: 3.6rem;
  line-height: 4.8rem;
margin-top: 0;
display: inline;
background: linear-gradient(transparent 75%, #f7d783 0%);
}
.puromycin-title02{
  font-size: 3.6rem;
  line-height: 4.8rem;
  margin-top: 0;
  display: inline;
  background: linear-gradient(transparent 75%, #f7d783 0%);
}
.puromycin-title03{
  font-size: 3.6rem;
  line-height: 4.8rem;
  margin-top: 0;
  display: inline;
  background: linear-gradient(transparent 75%, #f7d783 0%);
}

.text_title01 {
  text-align: left;
  font-size: clamp(2.2rem, 2.2vw, 2.7rem);
  margin-bottom: 0;
      margin: 10px 0;
}
.text_left01 {
font-size: 1.4rem;
width: 50%;
}
.text_left03 {
  font-size: 1.4rem;
  }
  
.fv01-img01{
  border: #ccc solid 1px;
}
.fv01{
  padding: 0;

}

.electrodes-img01 img{
  margin-top: 30px;
   }

.puromycin-background02 {
  padding: 0!important;
}
/*.border01{
  position: absolute;
  width: 30px;
  border: 5px solid red;
  height: 35vh;
  z-index: 10000;
  left: 76%;
}*/

.makerimg02 p {
  text-align: left;
  color: #3f3f3f;

  font-size: 1.6rem;
  line-height: 2.4rem;
}

.puromycin-flex-inner01{
  width: 100%!important;
  padding-top: 1rem!important;
}

.footer-flex{
  display: block;
}

.puromycin-text03{
  font-size: 1.4em;
  color: #3f3f3f;
  margin: 0 10px;

}
.puromycin-flex-button01{
  display: block;
}

.puromycin-inner-button01{
  margin: 0 auto;
  width:100% !important;
  display: block;
  margin-bottom: 40px;
}
.puromycin-logo-inner01 img{
width: 100%;
padding-left: 0;

}

.puromycin-flex-inner05{
  width: calc( 100% - 5px )!important;
  margin: 0 auto;
}

.puromycin-main-title01{
  margin: 20px 0;
}

.fv-makerimg02{
margin-bottom: 20px;
}

.fv-makerimg02 .puromycin-main-title01{
width: 100%;
}
.fv-makerimg02 .puromycin-background01{
  width: 100%;
}
.puromycin-background01{
  text-align: center;
  margin-top: 10px;
}
.fv-makerimg03{
  display: block;
}

.heading_title01{
  color: #fff;

  margin: 0 0 10px 0;

  
}
.puromycin-fv-text01{
  color: #fff!important;
  font-size: 2.4rem!important;
  line-height: 3.0rem!important;
  margin-bottom: 20px;
  font-weight: bold;
  line-height: normal;

}
.puromycin-fv-text02{
  color: #f1ae00!important;
    font-size: 5.5rem !important;
    text-align: center;
    margin-bottom: 20px;
}

.puromycin-pic01 img{
  width: 70%;
  text-align: center;
}
.puromycin-flex-inner06{
  width: 100%!important;
}
.makerimg04 {
  margin-bottom: 0px;
   width: 100%!important;
   display:flex; 
   justify-content:space-evenly;
   /*flex-flow:row wrap;*/
 }
 .puromycin-text06{
  font-size: 1.28em;
  margin-top: 5px;
 }
 .puromycin-flex-inner07{
  width: calc( 60% - 5px )!important;
}

.puromycin-flex-inner08{
  width: calc( 40% - 5px )!important;
}
.puromycin-flex-inner03{
  width: auto;
  border-radius: 50px;
  padding: 0.5rem 3rem;
  padding-bottom: 60px;
  padding-top: 2rem;
}

.puromycin-pic01-hide-sp{
  display: none;
}
.puromycin-pic01-hide-pc{
  display: block;
  margin-bottom: 60px;
}

table {
  overflow: auto;
  white-space: normal;
  display: block;
  overflow-x: scroll;
}

.puromycin-text-button01{
  text-decoration: none;
  color: #FFFFFF;
  font-size: 2.3rem;
  line-height: 2.4rem;
}
.puromycin-button01{
  padding: 25px;
}
.puromycin-text-button02{
  text-decoration: none;
  color: #FFFFFF;
  font-size: 2.3rem;
  line-height: 2.4rem;
}
.puromycin-button02{
  padding: 25px;
}
.puromycin-text04{
  font-size: 1.6rem;
  line-height: 2.4rem;
}
.puromycin-bold-text01-01{
  margin-bottom: 0rem!important;
  }
  .puromycin-flex-inner02{
    width: calc( 30% - 5px );
    width: 100% !important;
    /border: greenyellow solid 1px;
  }
}



@media screen and (max-width: 480px) {
  p, li{
    font-size: 1.62rem;
  }

  .fv01{

  }
  
  .makerimg02{
    display: block;
  }
  .makerimg02 div{
    width: calc( 98% - 0px );
    margin-bottom:0px;

  }
  .makerimg03{
    display: block;
  }
  .makerimg03 div{
    width: calc( 98% - 0px );
    margin-bottom: 0;
    padding-left: 0;
  }
 
  .text_title01 {
    text-align: left;
    font-size: clamp(2.2rem, 2.2vw, 2.7rem);
  }
  .text_left01 {
  font-size: 1.4rem;
  width: 82%;
  }
  .text_left03 {
    font-size: 1.4rem;
    }
    .button01{
      display: block;
      padding: 18px 60px;
      font-size: 1.6rem;
      line-height: 1.43;
      background: #4472C4;
      color: #3f3f3f;
     /* border-radius: 50px; */
      margin: 0 0px 40px ;
    
    }
    .fv01-img01{
      border:none;
      margin: 0;
    }
    header{
      margin: 0;
    }
    .makerimg02 p {
      text-align: left;
      color: #3f3f3f;
      line-height: 2.4rem;
      font-size: 1.6rem;
    }
    .logo01 {
   margin-bottom: 0;
   padding: 5px;

  }
    .logo02 {
      padding: 15px 10px;
      align-items: center;
      display: flex;
      width: 100%;
  }
    .logo02 img{
      height: 42px;
    }
    .logo03{
      margin-bottom: 0;
      padding: 10px;
    }
    .logo03 img{
      height: 50px;
    }
    .puromycin-title01{
      font-size: 3.2rem;
    }
    .puromycin-title02{
      font-size: 3.2rem;
    }
    .puromycin-title03{
      font-size: 3.2rem;
    }
    .puromycin-text-button01{
      font-size: 2.1rem;
    }
    .puromycin-inner-button01{
      margin: 0 auto;
      width:100% !important;
      display: block;

    }

    .puromycin-text-button02{
      font-size: 2.1rem;
    }
    .puromycin-fv-text01{
      color: #fff !important;
        font-size: 1.6rem !important;
        margin-bottom: 20px;
        font-weight: bold;
        line-height: 2.9rem !important;
        line-height: normal;

    }

    .puromycin-fv-text02{
      color: #f1ae00!important;
        font-size: 4.5rem !important;
        text-align: center;
        margin-bottom: 20px;
        line-height: 1;
    }
    .makerimg04 {
      margin-bottom: 0px;
       width: 100%!important;
       display: flex;
       /*flex-flow:row wrap;*/
     }
     .fv-makerimg02{
      display: flex;
      
     }
     .fv-makerimg03{
      display: block;
      margin: 0;
    }
    
     .fv-makerimg02 .puromycin-background01{
      width: 100%;
      padding: 0 10px;
      text-align: center;
    }

    .puromycin-logo-inner01 img{
      width: 100%;
    }
    h1 {
      color: #3f3f3f;
      font-size: 40px;
      line-height: 3rem;
      font-weight: bold;
      margin: 0 0 20px 0;
      padding: 0 0 5px 0;
  }
  .fv-makerimg02 .puromycin-main-title01{
    margin-right: 0;
  }
  .puromycin-main-title01{
    margin: 10px 0;
  }
  .puromycin-text05{
    line-height: normal!important;
  }
  .puromycin-text06{
    line-height: 1.7!important;
    padding-left: 10px;
    font-size: 1.16em;
    white-space: nowrap;
    margin-top: -13px;
  }

  .puromycin-flex-button01{
    display: block;

  }
  .puromycin-flex-inner03 {
    width: auto;
    border-radius: 50px;
    padding: 3rem 2rem;
    padding-bottom: 60px;
  }

  .puromycin-button01{

  /* height: 100px; */
  background: url(../images/03_01_puromycin_button01.png) no-repeat center center;
  background-size: contain;
  font-size: 2.8rem;
  line-height: 2.4rem;
  font-weight: bold;
  text-align: center;
  display: block !important;
  /* padding-top: 25px; */
  margin: 0 auto;
  padding: 25px;
  text-decoration: none;
  

}

.puromycin-button02{

  /* height: 100px; */
  background: url(../images/06_02_puromycin_button01.png) no-repeat center center;
  background-size: contain;
  font-size: 2.8rem;
  font-weight: bold;
  text-align: center;
  display: block !important;
  /* padding-top: 25px; */
  margin: 0 auto;
  padding: 25px;
  text-decoration: none;
}

.puromycin-section02{
  /*  background:#F2F2F2;*/
  margin-bottom: 4em;
  background: #fff;
  }

  .fv-makerimg02{
    margin-bottom: 5px;
  }
  .puromycin-flex-inner05 {
    width: 100%;
}
.puromycin-flex-inner07{
  width: calc(55% - 0px) !important;
}
.puromycin-flex-inner08{
  width: calc(45% - 0px) !important;
}
.puromycin-pic01 img{
  width: 60%;
  text-align: center;
}

.footer-flex {

  margin: 10px auto;

}
.items-border {
  /*border: solid 1px #3f3f3f;*/
  border-radius: 30px;
  padding: 8px 15px;
  margin: 0 ;

}
.puromycin-flex-inner03 table {
  width: 100%;
  table-layout: fixed;
  word-break: break-all;
  word-wrap: break-all;
}
.puromycin-flex-inner03 th{
  font-size: 1.2rem;
  text-align: center;
  background: #efefef;
  padding: 1em;
  border: 1px solid #ccc;
  width: 33%;
}
.puromycin-flex-inner03 td{
  font-size: 1.2rem;
  text-align: left;
  background: #ffffff;
  padding: 1em;
  border: 1px solid #ccc;
  font-weight: bold;
}
.kaigyou {
  display: inline-block;
}
.puromycin-flex-inner02{
  width: calc( 30% - 5px );
  width: 100% !important;
  /border: greenyellow solid 1px;
}
}