別品名 |
4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]- 1H-imidazol-4-yl]pyridine.
|
純度 |
>99%
|
分子量 |
377.44
|
CAS RN® |
152121-47-6
|
化合物の概要 |
A MAPK Homologue-p38 Inhibitor
|
構造 |
C21H16FN3OS
|
溶媒 |
DMSO
|
形状 |
凍結乾燥品
|
※サムネイル画像をクリックすると拡大画像が表示されます。
ManufacturerBioassayAlomone Labs SB 203580 inhibits the phosphorylation of Elk1 and Atf2 via p38 in 3T3-L1 cells. - Cells were grown to 70% confluence and serum starved for 3 h. The cells were then incubated for 2 h with various concentrations of?SB 203580?(#S-370) and stimulated with 5 μM?Anisomycin?(#A-520). Cell proteins were resolved by SDS-PAGE and probed with anti-phospho-p38 MAPK, antip38 MAPK, anti-phospho-Elk1 and anti-phospho-Atf2 as indicated. The phosphorylation of Elk1 and Atf2 decreased in a dose-dependent manner.
|
|
ManufacturerBioassayAlomone Labs SB 203580 inhibits the phosphorylation of Elk1 and Atf2 via p38 in 3T3-L1 cells. - Cells were grown to 70% confluence and serum starved for 3 h. The cells were then incubated for 2 h with various concentrations of?SB 203580?(#S-370) and stimulated with 5 μM?Anisomycin?(#A-520). Cell proteins were resolved by SDS-PAGE and probed with anti-phospho-p38 MAPK, antip38 MAPK, anti-phospho-Elk1 and anti-phospho-Atf2 as indicated. The phosphorylation of Elk1 and Atf2 decreased in a dose-dependent manner.
|
|
|
メーカー |
品番 |
包装 |
ALO
|
S-370
|
1 MG
|
※表示価格について
当社在庫 |
なし
|
納期目安 |
約10日
|
保存温度 |
-20℃
|
|