励起波長 |
385
|
蛍光波長 |
502
|
分子量 |
230.14
|
CAS RN® |
575-03-1
|
溶媒 |
DMSO
|
参考文献 |
Chang TK, Crespi CL, Waxman DJ.. (2006). Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes. Methods Mol Biol, 320, 97. Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.. (2004). Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases. Drug Metab Dispos, 32, 587. Dean B, Arison B, Chang S, Thomas PE, King C.. (2004). Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver. Arch Biochem Biophys, 426, 55. Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.. (2004). Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil). Drug Metab Dispos, 32, 267. Ekins S, Berbaum J, Harrison RK.. (2003). Generation and validation of rapid computational filters for cyp2d6 and cyp3a4. Drug Metab Dispos, 31, 1077. Jinno H, Saeki M, Tanaka-Kagawa T, Hanioka N, Saito Y, Ozawa S, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J.. (2003). Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10. Drug Metab Dispos, 31, 528. Huynh HT, Teel RW.. (2002). Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity. Anticancer Res, 22, 1699. Renwick AB, Lavignette G, Worboy PD, Williams B, Surry D, Lewis DF, Price RJ, Lake BG, Evans DC.. (2001). Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica, 31, 861. Renwick AB, Lewis DF, Fulford S, Surry D, Williams B, Worboys PD, Cai X, Wang RW, Price RJ, Lake BG, Evans DC.. (2001). Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4. Xenobiotica, 31, 187. Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.. (2000). Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms. Xenobiotica, 30, 955. Price RJ, Surry D, Renwick AB, Meneses-Lorente G, Lake BG, Evans DC.. (2000). CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes. Xenobiotica, 30, 781. Morse MA, Lu J.. (1998). High-performance liquid chromatographic method for measurement of cytochrome P450-mediated metabolism of 7-ethoxy-4-trifluoromethylcoumarin. J Chromatogr B Biomed Sci Appl, 708, 290. Ekins S, Vandenbranden M, Ring BJ, Gillespie JS, Yang TJ, Gelboin HV, Wrighton SA.. (1998). Further characterization of the expression in liver and catalytic activity of CYP2B6. J Pharmacol Exp Ther, 286, 1253. Ekins S, VandenBranden M, Ring BJ, Wrighton SA.. (1997). Examination of purported probes of human CYP2B6. Pharmacogenetics, 7, 165.
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使用文献 |
Chang TK Crespi CL, Waxman DJ. (2006). Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes. Methods Mol Biol, 97.
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[注意事項] |
湿気を防ぎ、遮光して保存
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※表示価格について
当社在庫 |
なし
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納期目安 |
1週間程度
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保存温度 |
-20℃
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